Candida auris-associated hospitalizations and outbreaks, China, 2018-2023.

Candida auris-associated hospitalizations and outbreaks, China, 2018-2023.
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DOI:
10.1080/22221751.2024.2302843
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发表时间:
2024-12
影响因子:
13.2
通讯作者:
--
中科院分区:
医学2区
文献类型:
--
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新出现的人类真菌病原体耳念珠菌已成为严重威胁公共卫生的一个重要因素。截至2023年12月,该病原体已蔓延至中国10个省份。这里我们描述312 C。2018年至2023年,中国的耳相关住院和4起医疗机构疫情。C.在此期间,已经确定了耳道。分子流行病学分析表明,C。在中国,已经有多起地方传播。大部分C。中国分离的耳癣菌对氟康唑耐药率为98.7%,对阿替霉素B和卡泊芬净耐药率分别为4.2%和2.2%。
The emerging human fungal pathogen Candida auris has become a serious threat to public health. This pathogen has spread to 10 provinces in China as of December 2023. Here we describe 312 C. auris-associated hospitalizations and 4 outbreaks in healthcare settings in China from 2018 to 2023. Three genetic clades of C. auris have been identified during this period. Molecular epidemiological analyses indicate that C. auris has been introduced and local transmission has occurred in multiple instances in China. Most C. auris isolated from China (98.7%) exhibited resistance to fluconazole, while only a small subset of strains were resistant to amphotericin B (4.2%) and caspofungin (2.2%).
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