High-resolution sodium imaging of human brain at 7 T.
High-resolution sodium imaging of human brain at 7 T.
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DOI：
10.1002/mrm.23225
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发表时间：
2012-07
影响因子：
3.3
通讯作者：
Boada, Fernando E.
中科院分区：
文献类型：
--
作者：
Qian, Yongxian;Zhao, Tiejun;Zheng, Hai;Weimer, Jonathan;Boada, Fernando E.
本研究证明了在7 T条件下对人脑进行高分辨率钠MRI的可行性。三维各向异性分辨率数据采集被用来解决与高分辨率相关联的低SNR的挑战。各向异性数据采集采用超短回波时间序列。在全身7 T MRI扫描仪上研究了正常人和健康人的大脑。钠图像在两个高标称平面内分辨率（1.72和0.86 mm），层厚4 mm。脑图像（脑脊液）的SNR测量为14.4和6.8，分别在两个高分辨率。实际面内分辨率测量为2.9和1.6 mm，比其标称值大69-86%。由于平面内分辨率的改善，体模和脑图像上的钠浓度定量在高标称分辨率下比在低标称分辨率3.44 mm（测量分辨率5.5 mm）下具有更好的准确度。
The feasibility of high resolution sodium MRI on human brain at 7T was demonstrated in this study. A three-dimensional anisotropic resolution data acquisition was used to address the challenge of low SNR associated with high resolution. Ultrashort echo time sequence was employed for the anisotropic data acquisition. Phantoms and healthy human brains were studied on a whole-body 7T MRI scanner. Sodium images were obtained at two high nominal in-plane resolutions (1.72 and 0.86 mm) at slice thickness 4 mm. SNR in the brain image (cerebrospinal fluid) was measured as 14.4 and 6.8 at the two high resolutions, respectively. The actual in-plane resolution was measured as 2.9 and 1.6 mm, 69–86% larger than their nominal values. The quantification of sodium concentration on the phantom and brain images enabled better accuracy at the high nominal resolutions than at the low nominal resolution 3.44 mm (measured resolution 5.5 mm) due to the improvement of in-plane resolution.
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影响因子：
3.3
作者：
Gurney, PT;Hargreaves, BA;Nishimura, DG
通讯作者：
Nishimura, DG
影响因子：
14.5
作者：
Inglese, M.;Madelin, G.;Johnson, G.
通讯作者：
Johnson, G.
影响因子：
2.3
作者：
Thulborn, KR;Davis, D;Kassam, A
通讯作者：
Kassam, A
DOI：
10.1007/s10334-006-0028-0
发表时间：
2006-05-01
影响因子：
2.3
作者：
Mentrup, D;Eggers, H
通讯作者：
Eggers, H
影响因子：
10.6
作者：
JACKSON, JI;MEYER, CH;MACOVSKI, A
通讯作者：
MACOVSKI, A