Assessment of right ventricular regional contraction and comparison with the left ventricle in normal humans: a cine magnetic resonance study with presaturation myocardial tagging.
Assessment of right ventricular regional contraction and comparison with the left ventricle in normal humans: a cine magnetic resonance study with presaturation myocardial tagging.
复制标题
正常人右心室区域收缩的评估及其与左心室的比较：预饱和心肌标记的电影磁共振研究。
作者：
H. Naito;J. Arisawa;Koushi Harada;H. Yamagami;T. Kozuka;S. Tamura
目的--右心室局部收缩力一直被认为难以精确评估。采用预饱和心肌标记的电影磁共振成像来定量右心室游离壁的收缩，并与左心室相比识别正常性能。方法：9名正常志愿者，年龄27-39岁，在1.5特斯拉磁共振磁铁中进行检查，短轴和四腔室切面在心室中段水平进行电影磁共振序列成像。标记，在端孔处应用为两条平行黑线，标记游离壁的中部，在短轴切片中将其分为上段、中段和下段，在四腔切片中将其分为前段、中段和后段。从心动周期内50 ms间隔的一系列电影磁共振图像中，选择舒张末期和收缩早期、中期和末期图像，用于计算6个节段的心内膜、心外膜和平均缩短百分比（%FS）。结果：（1）收缩期两个切面的%FS均逐渐增加（2）跨壁收缩力梯度差;（3）肌间短缩占优势（全长，平均收缩末期%FS（SD）：短轴，17.4（3.1）%;四腔，30.1（4.1）%，P < 0.001），而左室侧壁以周向缩短为主;（4）短轴切面收缩优势较低（P < 0.001），四腔切面收缩优势居中（P < 0.005）。结论：收缩力的异质性与心肌纤维结构密切相关，并与由其厚度和曲率决定的壁应力密切相关。结果表明，采用心肌标记法的电影磁共振成像技术可以无创地评价右心室局部功能。
OBJECTIVE--Right ventricular regional contractility has been thought to be difficult to assess precisely. Cine magnetic resonance imaging with presaturation myocardial tagging was employed to quantitate the contraction of the right ventricular free wall and to identify normal performance compared with the left ventricle. METHODS--Nine normal volunteers, aged 27-39 years, were examined in a 1.5 Tesla superconductive magnet, and short axis and four-chamber sections at the mid-ventricular level were imaged with cine magnetic resonance sequences. Tags, applied at end diastole as two parallel black lines, intersected the mid-portion of the free wall, dividing it into upper, centre, and lower segments in the short axis section, and anterior, middle, and posterior segments in the four-chamber section. From a series of cine magnetic resonance images at 50 ms intervals over a cardiac cycle, end diastolic, and early, mid-, and end systolic images were chosen for calculation of the endocardial, epicardial, and mean percent fractional shortening (%FS) in the six segments. RESULTS--There was (1) a gradual increase in %FS in systole in both sections (P < 0.001, < 0.005); (2) a poor transmural gradient of contractility; (3) a predominance of meridional shortening (whole length, mean end systolic %FS (SD): short axis, 17.4 (3.1)%; four-chamber, 30.1 (4.1)%; P < 0.001) in contrast to dominant circumferential shortening in the left ventricular lateral wall; (4) lower predominance of contractility in the short axis section (P < 0.001), and a middle dip of contractility in the four-chamber section (P < 0.005). CONCLUSIONS--Heterogeneity of contractility was closely correlated with the myocardial fibre architecture, and with wall stress determined by its thickness and curvature. It was proved that right ventricular regional function could be analysed non-invasively using cine magnetic resonance imaging with myocardial tagging.
DOI：
10.1152/ajpheart.1985.249.2.h241
发表时间：
1985
期刊：
The American journal of physiology
影响因子：
--
作者：
Gallagher,KP;Osakada,G;Matsuzaki,M;Miller,M;Kemper,WS;RossJr,J
通讯作者：
RossJr,J
运动犬缺血时心内膜下和心外膜下壁增厚。
影响因子：
37.8
作者：
Homans,DC;Sublett,E;Lindstrom,P;Nesbitt,T;Bache,RJ
通讯作者：
Bache,RJ