Organization of sensory feature selectivity in the whisker system.
Organization of sensory feature selectivity in the whisker system.
复制标题
DOI：
10.1016/j.neuroscience.2017.09.014
复制
发表时间：
2018-01-01
期刊：
影响因子：
3.3
通讯作者：
Maravall M
中科院分区：
文献类型：
--
作者：
Bale MR;Maravall M
触须系统中的神经元对感觉刺激的空间和动力学特性（特征）具有选择性。在通路的每个阶段，不同的神经元编码不同的特征，产生丰富的群体表示。胡须触摸是鲁棒的代表;神经元响应触摸驱动的快速波动的力量在胡须基地。皮层神经元比皮层下神经元具有更复杂和更依赖于上下文的选择性，例如，to collective集体whisper胡须motion运动.了解这些信号如何整合以构建触须介导的感知需要进一步的研究。我们的感觉受体面临着不同环境输入的冲击。每一个感觉事件或与物体的相遇都涉及到撞击感受器的物理能量源的独特组合。在啮齿类动物的胡须系统中，位于三叉神经节的每个初级传入神经元支配并响应单个胡须，并编码一组不同的物理刺激特性-特征-对应于胡须角度和形状的变化以及随后作用于胡须毛囊的力。在这里，我们审查的性质编码的功能连续阶段的处理沿着晶须途径。在每个阶段，不同的神经元会对不同的特征做出反应，因此整个群体代表不同的属性。不同的神经元类型也具有不同的特征选择性。因此，处于处理和响应相同胡须的相同阶段的神经元在代表胡须接触的物体时扮演不同的角色。这种多样性，加上精确的时间和高可靠性的反应，使人口在每个阶段代表了广泛的刺激。皮层神经元对更复杂的刺激特性的反应--比如胡须上的相关运动--比早期皮层下阶段的反应要复杂得多。沿着这条通路的时间整合沿着是比较弱的：神经元桶皮质（BC）主要是敏感的快速（几十毫秒）的波动，在晶须运动。触须敏感性的地形组织是由神经元对某些其他物理特征的选择性的系统组织来描述的，但是对触摸和动态刺激特性的选择性以“盐和胡椒”的方式分布。
Neurons in the whisker system are selective to spatial and dynamical properties – features – of sensory stimuli. At each stage of the pathway, different neurons encode distinct features, generating a rich population representation. Whisker touch is robustly represented; neurons respond to touch-driven fast fluctuations in forces at the whisker base. Cortical neurons have more complex and context-dependent selectivity than subcortical, e.g., to collective whisker motion. Understanding how these signals are integrated to construct whisker-mediated percepts requires further research. Our sensory receptors are faced with an onslaught of different environmental inputs. Each sensory event or encounter with an object involves a distinct combination of physical energy sources impinging upon receptors. In the rodent whisker system, each primary afferent neuron located in the trigeminal ganglion innervates and responds to a single whisker and encodes a distinct set of physical stimulus properties – features – corresponding to changes in whisker angle and shape and the consequent forces acting on the whisker follicle. Here we review the nature of the features encoded by successive stages of processing along the whisker pathway. At each stage different neurons respond to distinct features, such that the population as a whole represents diverse properties. Different neuronal types also have distinct feature selectivity. Thus, neurons at the same stage of processing and responding to the same whisker nevertheless play different roles in representing objects contacted by the whisker. This diversity, combined with the precise timing and high reliability of responses, enables populations at each stage to represent a wide range of stimuli. Cortical neurons respond to more complex stimulus properties – such as correlated motion across whiskers – than those at early subcortical stages. Temporal integration along the pathway is comparatively weak: neurons up to barrel cortex (BC) are sensitive mainly to fast (tens of milliseconds) fluctuations in whisker motion. The topographic organization of whisker sensitivity is paralleled by systematic organization of neuronal selectivity to certain other physical features, but selectivity to touch and to dynamic stimulus properties is distributed in “salt-and-pepper” fashion.
登录
查看更多内容
影响因子：
25
作者：
Cruikshank, Scott J.;Lewis, Timothy J.;Connors, Barry W.
通讯作者：
Connors, Barry W.
影响因子：
25
作者：
Bandyopadhyay, Sharba;Shamma, Shihab A.;Kanold, Patrick O.
通讯作者：
Kanold, Patrick O.
影响因子：
3.5
作者：
Bale MR;Ince RA;Santagata G;Petersen RS
通讯作者：
Petersen RS
影响因子：
2.5
作者：
Bale, Michael R.;Petersen, Rasmus S.
通讯作者：
Petersen, Rasmus S.
影响因子：
16.2
作者：
Aljadeff J;Lansdell BJ;Fairhall AL;Kleinfeld D
通讯作者：
Kleinfeld D