Changes in childhood vaccination during the coronavirus disease 2019 pandemic in Japan.
Changes in childhood vaccination during the coronavirus disease 2019 pandemic in Japan.
复制标题
DOI：
10.1016/j.vaccine.2021.05.050
复制
发表时间：
2021-06-29
期刊：
影响因子：
5.5
通讯作者：
Saitoh A
中科院分区：
文献类型：
--
作者：
Aizawa Y;Katsuta T;Sakiyama H;Tanaka-Taya K;Moriuchi H;Saitoh A
2019 年冠状病毒病（COVID-19）大流行极大地影响了日常生活。 COVID-19 通常会导致儿童出现无症状或轻度疾病；然而，儿童常规免疫接种的延迟令人担忧，因为这可能会增加疫苗可预防疾病的风险。尚无研究评估 COVID-19 大流行期间日本儿童疫苗接种情况。这项回顾性观察研究评估了 2016 年至 2020 年期间日本 4 个城市（东京都市区的 2 个城市和远离东京的 2 个城市）儿童接种的疫苗剂量。按月比较了 2020 年 1 月至 9 月在 COVID-19 大流行期间接种的疫苗剂量与 2016 年至 2019 年期间接种的疫苗剂量。收集按年龄分层的人口统计数据，以确定除儿童人口随时间变化以外的其他因素是否会影响疫苗接种趋势。在所有城市中，疫苗接种剂量的减少在 2020 年 3 月和 4 月最为明显，即在 2020 年 4 月 7 日宣布全国范围内的 COVID-19 紧急状态之前或同时。东京都市区早在 2 月份就开始减少。随着孩子年龄的增长，这种下降更加明显。 5月25日国家紧急状态解除前，各城市各年龄组疫苗接种情况均出现了追赶。老年组的疫苗剂量持续增加，但婴儿的疫苗剂量却没有增加。 4个城市的总体疫苗接种趋势没有显着差异。 COVID-19 大流行严重影响了日本的常规儿童免疫接种。因此，有必要建立全国性的电子监控系统并向监护人发布公告，以鼓励及时进行常规免疫接种。
The coronavirus disease 2019 (COVID-19) pandemic has greatly affected daily life. COVID-19 often causes asymptomatic or mild disease in children; however, delayed routine childhood immunization is a concern, as it could increase the risk of vaccine-preventable disease. No study has evaluated the status of childhood vaccinations in Japan during the COVID-19 pandemic. This retrospective observational study evaluated the number of vaccine doses administered to children in 4 Japanese cities (2 cities in the Tokyo metropolitan area and 2 cities far from Tokyo) during the period from 2016 to 2020. Vaccine doses administered between January and September 2020 during the COVID-19 pandemic were compared, by month, with those given during 2016–2019. Age-stratified demographic data were collected to determine whether factors other than change in the child population over time affected vaccination trends. In all cities the decrease in vaccine doses administered was most apparent in March and April 2020, i.e., just before or coincident with the declaration of a nationwide COVID-19 emergency on April 7, 2020. The decrease started as early as February in the Tokyo metropolitan area. As child age increased, the decrease became more apparent. Before the lift of national emergency on May 25, catch-up of the vaccination was observed in all age groups in all cities. Vaccine doses persistently increased in older age groups but not in infants. The overall vaccination trends did not differ significantly among the 4 cities. The COVID-19 pandemic significantly affected routine childhood immunization in Japan. Thus, a nationwide electronic surveillance system and announcements for guardians to encourage timely routine immunization are warranted.
登录
查看更多内容
影响因子：
13.8
作者：
Place R;Lee J;Howell J
通讯作者：
Howell J
影响因子：
2.2
作者：
Kakuya, Fujio;Okubo, Hitoshi;Kinebuchi, Takahiro
通讯作者：
Kinebuchi, Takahiro
影响因子：
19
作者：
McDonald, Helen, I;Tessier, Elise;Edelstein, Michael
通讯作者：
Edelstein, Michael
影响因子：
5.5
作者：
Saitoh, Akihiko;Okabe, Nobuhiko
通讯作者：
Okabe, Nobuhiko
影响因子：
5.5
作者：
Middeldorp M;van Lier A;van der Maas N;Veldhuijzen I;Freudenburg W;van Sorge NM;Sanders EAM;Knol MJ;de Melker HE
通讯作者：
de Melker HE