Synergy of understanding dermatologic disease and epidermal biology.

Synergy of understanding dermatologic disease and epidermal biology.
复制标题

了解皮肤病和表皮生物学的协同作用。

DOI:
10.1172/jci62237
复制
发表时间:
2012
期刊:
The Journal of clinical investigation
影响因子:
--
通讯作者:
Stanley,JohnR
Stanley,JohnR
中科院分区:
--
文献类型:
--
作者:
Stanley,JohnR

文献摘要

参考文献

被引文献

相似文献

皮肤病,虽然很少危及生命,但可以严重毁容和干扰生活质量。此外,与其他器官相反,皮肤及其附属结构毛囊的老化会导致影响我们大多数人的美容问题。本皮肤病学综述系列中的文章展示了在理解表皮和毛囊的细胞生物学和分子病理生理学方面的最新进展,表皮和毛囊含有角质形成细胞和黑素细胞干细胞。它们揭示了研究和临床护理之间的动态关系:皮肤病的知识促进了对表皮生物学的理解,反过来,基础科学的进步也为我们对疾病的理解提供了信息。这种类型的协同作用是JCI致力于出版的临床研究的一个深刻的力量。
Dermatologic disease, although seldom life threatening, can be extremely disfiguring and interfere with the quality of life. In addition, as opposed to other organs, just the aging of skin and its adnexal structure the hair follicle can result in cosmetic concerns that affect most of us. The articles in this dermatology Review Series demonstrate recent progress in understanding the cell biology and molecular pathophysiology of the epidermis and hair follicles, which harbor keratinocyte and melanocyte stem cells. They reveal a dynamic relationship between research and clinical care: knowledge of dermatologic disease has facilitated the understanding of the biology of the epidermis and, in turn, progress in basic science has informed our understanding of disease. This type of synergy is a profound strength of clinical research of the type that theJCIis dedicated to publishing.
DOI: 10.1126/science.1099593
发表时间: 2005-02-04
期刊: SCIENCE
影响因子: 56.9
作者:
Nishimura, EK;Granter, SR;Fisher, DE
通讯作者: Fisher, DE
DOI: 10.1158/0008-5472.can-09-2976
发表时间: 2009-12-15
期刊: Cancer research
影响因子: 11.2
作者:
Zhao L;Li W;Marshall C;Griffin T;Hanson M;Hick R;Dentchev T;Williams E;Werth A;Miller C;Bashir H;Pear W;Seykora JT
通讯作者: Seykora JT
癌基因和抑癌基因在多阶段癌发生中的作用。
DOI: --
发表时间: 1994
影响因子: 6.5
作者:
S. H. Yuspa;A. A. Dlugosz;Christina K. Cheng;M. F. Denning;T. Tennenbaum;Adam B. Glick;Wendy C. Weinberg
通讯作者: Wendy C. Weinberg
DOI: 10.1038/jid.1962.97
发表时间: 1962
期刊: The Journal of investigative dermatology
影响因子: --
作者:
R. Staricco;A. MILLER
通讯作者: A. MILLER
DOI: 10.1172/jci46307
发表时间: 2011-05-01
影响因子: 15.9
作者:
Grachtchouk, Marina;Pero, Joanna;Dlugosz, Andrzej A.
通讯作者: Dlugosz, Andrzej A.