Biology of Radiation-Induced Lung Injury.

Biology of Radiation-Induced Lung Injury.
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DOI:
10.1016/j.semradonc.2020.11.006
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发表时间:
2021-04
影响因子:
3.5
通讯作者:
Citrin DE
Citrin DE
中科院分区:
医学2区
文献类型:
--
作者:
Roy S;Salerno KE;Citrin DE

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辐射诱导的肺损伤(RILI)包括辐射诱导的肺炎、可能表现为剂量限制性急性或亚急性毒性的肺部炎症,以及辐射诱导的肺纤维化、肺暴露于辐射的晚期效应。本文综述了放射性肺损伤的分子放射生物学研究进展及其临床意义
Radiation induced lung injury (RILI) encompasses radiation induced pneumonitis, inflammation of the lung which may manifest as a dose-limiting acute or sub-acute toxicity, and radiation induced lung fibrosis, a late effect of lung exposure to radiation. This review aims to highlight developments in molecular radiation biology of radiation induced lung injury and their implications in clinical practice
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