Modelling the spread of American foulbrood in honeybees.

Modelling the spread of American foulbrood in honeybees.
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DOI:
10.1098/rsif.2013.0650
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发表时间:
2013-11-06
期刊:
Journal of the Royal Society, Interface
影响因子:
--
通讯作者:
Keeling MJ
Keeling MJ
中科院分区:
其他
文献类型:
--
作者:
Datta S;Bull JC;Budge GE;Keeling MJ

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We investigate the spread of American foulbrood (AFB), a disease caused by the bacterium Paenibacillus larvae, that affects bees and can be extremely damaging to beehives. Our dataset comes from an inspection period carried out during an AFB epidemic of honeybee colonies on the island of Jersey during the summer of 2010. The data include the number of hives of honeybees, location and owner of honeybee apiaries across the island. We use a spatial SIR model with an underlying owner network to simulate the epidemic and characterize the epidemic using a Markov chain Monte Carlo (MCMC) scheme to determine model parameters and infection times (including undetected ‘occult’ infections). Likely methods of infection spread can be inferred from the analysis, with both distance- and owner-based transmissions being found to contribute to the spread of AFB. The results of the MCMC are corroborated by simulating the epidemic using a stochastic SIR model, resulting in aggregate levels of infection that are comparable to the data. We use this stochastic SIR model to simulate the impact of different control strategies on controlling the epidemic. It is found that earlier inspections result in smaller epidemics and a higher likelihood of AFB extinction.
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