Ultrasonic attenuation estimation of the pregnant cervix: a preliminary report.
Ultrasonic attenuation estimation of the pregnant cervix: a preliminary report.
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DOI：
10.1002/uog.7643
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发表时间：
2010-08
影响因子：
7.1
通讯作者：
Abramowicz, J. S.
中科院分区：
文献类型：
--
作者：
McFarlin, B. L.;Bigelow, T. A.;Laybed, Y.;O'Brien, W. D., Jr.;Oelze, M. L.;Abramowicz, J. S.
超声衰减（超声波在组织中传播时的能量损失）的估计已用于评估健康和疾病中组织的结构和功能。本研究的目的是开发一种方法来估计超声宫颈衰减在人类怀孕期间使用临床超声系统。40名女性在妊娠期间使用Zonare® z.one临床超声系统（使用4-9-MHz阴道内探头）进行了一次宫颈扫描。该超声系统可访问射频（RF）图像数据进行处理和分析。此外，采集具有已知衰减系数的仿组织体模的扫描并用作参考。在参考扫描中使用了与临床扫描相同的设置和探头。波束形成图像的数字数据以医学数字成像和通信（DICOM）格式保存在闪存驱动器上，并使用Zonare提供的Matlab®程序在个人计算机上转换为RF数据。使用一种算法获得衰减估计值，该算法使用仿组织超声体模进行独立验证。采集并分析RF数据以估计人类妊娠子宫颈的衰减。回归分析显示，衰减是从超声检查到分娩的时间间隔的预测因子（β = 0.43，P = 0.01）;不是检查时胎龄的预测因子（β =-0.23，P = 0.15）;也不是宫颈长度的预测因子（β = 0.077，P = 0.65）。超声衰减估计有可能成为一种早期和客观的非侵入性方法来检测检查和分娩之间的间隔。我们假设需要更大的样本量和纵向研究设计来检测胎龄相关的宫颈衰减变化。
Estimates of ultrasonic attenuation (the loss of energy as an ultrasonic wave propagates through tissue) have been used to evaluate the structure and function of tissues in health and disease. The purpose of this research was to develop a method to estimate ultrasonic cervical attenuation during human pregnancy using a clinical ultrasound system. Forty women underwent a cervical scan once during pregnancy with the Zonare® z.one clinical ultrasound system using a 4–9-MHz endovaginal transducer. This ultrasound system provides access to radiofrequency (RF) image data for processing and analysis. In addition, a scan of a tissue-mimicking phantom with a known attenuation coefficient was acquired and used as a reference. The same settings and transducer used in the clinical scan were used in the reference scan. Digital data of the beam-formed image were saved in Digital Imaging and Communications in Medicine (DICOM) format on a flash drive and converted to RF data on a personal computer using a Matlab® program supplied by Zonare. Attenuation estimates were obtained using an algorithm that was independently validated using tissue-mimicking ultrasonic phantoms. RF data were acquired and analyzed to estimate attenuation of the human pregnant cervix. Regression analysis revealed that attenuation was: a predictor of the interval from ultrasound examination to delivery (β = 0.43, P = 0.01); not a predictor of gestational age at time of examination (β = −0.23, P = 0.15); and not a predictor of cervical length (β = 0.077, P = 0.65). Ultrasonic attenuation estimates have the potential to be an early and objective non-invasive method to detect interval between examination and delivery. We hypothesize that a larger sample size and a longitudinal study design will be needed to detect gestational age-associated changes in cervical attenuation.
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影响因子：
2.4
作者：
Hall, CS;Verdonk, ED;Miller, JG
通讯作者：
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