Hypertension and associated factors in HIV-infected patients receiving antiretroviral treatment in Burundi: a cross-sectional study.

Hypertension and associated factors in HIV-infected patients receiving antiretroviral treatment in Burundi: a cross-sectional study.
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DOI:
10.1038/s41598-022-24997-7
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发表时间:
2022-11-28
期刊:
影响因子:
4.6
通讯作者:
Desormais, Ileana
Desormais, Ileana
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Harimenshi, Deo;Niyongabo, Theodore;Preux, Pierre-Marie;Aboyans, Victor;Desormais, Ileana

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目前,人类免疫缺陷病毒(HIV)感染者的预期寿命与一般人群相似。高血压是非洲的一个主要公共卫生问题,但在很大程度上未得到充分诊断。大多数艾滋病毒感染者,特别是接受抗逆转录病毒治疗(ART)的人患有高血压。我们的项目旨在确定布隆迪接受抗逆转录病毒治疗的艾滋病毒感染成人中高血压的流行情况和相关因素。在五个艾滋病毒感染者保健中心(PLWH)管理的20岁以上艾滋病毒感染者中进行了一项横断面研究。采用世界卫生组织STEPWISE调查和人体测量法。根据ESC 2018年的建议测量血压。纳入1250例年龄在35.4 ~ 50.2岁之间的hiv感染者(男性18.4%)。高血压患病率为17.4% (95% CI 13.2-22.1)。大约47.25%的HIV合并高血压患者以前未被诊断。其他因素与HTN相关,如超重(OR 2.88; 95% CI 1.46-5.62)、肥胖(OR 2.65; 95% CI 1.27-5.55)、HIV感染持续时间更长:≥10年(OR 1.04; 95% CI 1.14-3.20)、糖尿病(OR 2.1; 95% CI 1.37-3.32)和年龄(OR 1.13; 95% CI 1.09-1.14)。尽管年龄很小,但接受艾滋病毒-抗逆转录病毒治疗的患者中有近20%患有高血压,其中50%未被诊断出来。血压监测对这些患者至关重要,特别是那些被确定为高风险的患者,需要及时采取挽救生命和残疾的干预措施。
Currently, the life expectancy of people living with the human immunodeficiency virus (HIV) and the general population are similar. Hypertension is a major public health issue in Africa and is largely underdiagnosed. Most HIV-infected individuals, especially those on Anti-Retroviral Therapy (ART) have hypertension. Our project aims to determine the prevalence of hypertension and associated factors amongst HIV-infected adults treated by ART in Burundi. A cross-sectional study was conducted among HIV-infected subjects over the age of 20, managed in five healthcare centers for people living with HIV (PLWH). The World Health Organization STEPWISE survey and anthropometric measurements were employed. Blood pressure was measured according to the ESC 2018 recommendations. 1 250 HIV-infected patients aged between 35.4 and 50.2 years were included (18.4% men). The prevalence of hypertension was 17.4% (95% CI 13.2–22.1). Approximately 47.25% of HIV patients with hypertension were previously undiagnosed. Other factors were associated with HTN, such as being overweight (OR 2.88; 95% CI 1.46–5.62), obesity (OR 2.65; 95% CI 1.27–5.55), longer duration of HIV infection: ≥ 10 years (OR 1.04; 95% CI 1.14–3.20), diabetes (OR 2.1; 95% CI 1.37–3.32) and age (OR 1.13; 95% CI 1.09–1.14). Despite their young age, almost 20% of HIV-ART treated patients had hypertension, 50% of these were undiagnosed. Blood pressure monitoring is crucial in these patients, especially those identified as high-risk, with prompt life and disability-saving interventions.
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