Defining necrotizing enterocolitis: current difficulties and future opportunities.

Defining necrotizing enterocolitis: current difficulties and future opportunities.
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DOI:
10.1038/s41390-020-1074-4
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发表时间:
2020-08
期刊:
影响因子:
3.6
通讯作者:
Caplan MS
Caplan MS
中科院分区:
医学3区
文献类型:
--
作者:
Patel RM;Ferguson J;McElroy SJ;Khashu M;Caplan MS

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坏死性小肠结肠炎(NEC)是住院婴儿发病率和死亡率的主要原因。1978年首次通过贝尔分期进行分类,在随后的几十年中提出了NEC的一些额外定义。在这篇综述中,我们总结了目前NEC的8种定义,并探讨了这些定义中包括的临床体征和放射学特征的异同,以及它们的局限性。我们强调在定义NEC方面达成全球共识的重要性,以改善NEC的研究和成果,并纳入国际NEC会议与会者的意见。我们还强调了患者家庭在帮助重新定义NEC方面的重要作用。
Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in hospitalized infants. First classified through Bell staging in 1978, a number of additional definitions of NEC have been proposed in the subsequent decades. In this review, we summarize 8 current definitions of NEC, and explore similarities and differences in clinical signs and radiographic features included within these definitions, as well as their limitations. We highlight the importance of a global consensus on defining NEC to improve NEC research and outcomes, incorporating input from participants at an international NEC conference. We also highlight the important role of patient-families in helping to redefine NEC.
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