Defining necrotizing enterocolitis: current difficulties and future opportunities.
Defining necrotizing enterocolitis: current difficulties and future opportunities.
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DOI:
10.1038/s41390-020-1074-4
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发表时间:
2020-08
影响因子:
3.6
通讯作者:
Caplan MS
中科院分区:
文献类型:
--
作者:
Patel RM;Ferguson J;McElroy SJ;Khashu M;Caplan MS
Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in hospitalized infants. First classified through Bell staging in 1978, a number of additional definitions of NEC have been proposed in the subsequent decades. In this review, we summarize 8 current definitions of NEC, and explore similarities and differences in clinical signs and radiographic features included within these definitions, as well as their limitations. We highlight the importance of a global consensus on defining NEC to improve NEC research and outcomes, incorporating input from participants at an international NEC conference. We also highlight the important role of patient-families in helping to redefine NEC.
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