IMG/VR: a database of cultured and uncultured DNA Viruses and retroviruses.
IMG/VR: a database of cultured and uncultured DNA Viruses and retroviruses.
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DOI:
10.1093/nar/gkw1030
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发表时间:
2017-01-04
影响因子:
14.9
通讯作者:
Kyrpides NC
中科院分区:
文献类型:
--
作者:
Paez-Espino D;Chen IA;Palaniappan K;Ratner A;Chu K;Szeto E;Pillay M;Huang J;Markowitz VM;Nielsen T;Huntemann M;K Reddy TB;Pavlopoulos GA;Sullivan MB;Campbell BJ;Chen F;McMahon K;Hallam SJ;Denef V;Cavicchioli R;Caffrey SM;Streit WR;Webster J;Handley KM;Salekdeh GH;Tsesmetzis N;Setubal JC;Pope PB;Liu WT;Rivers AR;Ivanova NN;Kyrpides NC
Viruses represent the most abundant life forms on the planet. Recent experimental and computational improvements have led to a dramatic increase in the number of viral genome sequences identified primarily from metagenomic samples. As a result of the expanding catalog of metagenomic viral sequences, there exists a need for a comprehensive computational platform integrating all these sequences with associated metadata and analytical tools. Here we present IMG/VR (https://img.jgi.doe.gov/vr/), the largest publicly available database of 3908 isolate reference DNA viruses with 264 413 computationally identified viral contigs from >6000 ecologically diverse metagenomic samples. Approximately half of the viral contigs are grouped into genetically distinct quasi-species clusters. Microbial hosts are predicted for 20 000 viral sequences, revealing nine microbial phyla previously unreported to be infected by viruses. Viral sequences can be queried using a variety of associated metadata, including habitat type and geographic location of the samples, or taxonomic classification according to hallmark viral genes. IMG/VR has a user-friendly interface that allows users to interrogate all integrated data and interact by comparing with external sequences, thus serving as an essential resource in the viral genomics community.
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DOI:
10.1038/ismej.2016.89
发表时间:
2017-01
期刊:
The ISME journal
影响因子:
--
作者:
Bolduc B;Youens-Clark K;Roux S;Hurwitz BL;Sullivan MB
通讯作者:
Sullivan MB
影响因子:
14.9
作者:
Clark K;Karsch-Mizrachi I;Lipman DJ;Ostell J;Sayers EW
通讯作者:
Sayers EW
DOI:
10.1073/pnas.0409727102
发表时间:
2005-02-15
影响因子:
11.1
作者:
Konstantinidis, KT;Tiedje, JM
通讯作者:
Tiedje, JM
影响因子:
11.3
作者:
Edwards RA;McNair K;Faust K;Raes J;Dutilh BE
通讯作者:
Dutilh BE
影响因子:
6.4
作者:
Paez-Espino D;Sharon I;Morovic W;Stahl B;Thomas BC;Barrangou R;Banfield JF
通讯作者:
Banfield JF