Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion
Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion
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穿心莲内酯增强慢性脑灌注不足大鼠模型中海马 BDNF 信号传导并抑制神经元凋亡、星形胶质细胞活化、神经炎症和空间记忆缺陷
DOI:
10.1007/s00210-019-01672-9
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发表时间:
2019-06
期刊:
影响因子:
--
通讯作者:
Jian Hai
中科院分区:
文献类型:
--
作者:
Da-Peng Wang;Hang Yin;Qi Lin;Shu-Ping Fang;Jian-Hua Shen;Yi-Fang Wu;Shao-Hua Su;Jian Hai
Andrographolide is a medical herbal compound with documented anti-inflammatory activity and therapeutic efficacy in animal models of Alzheimer’s disease, traumatic brain injury, and ischemic stroke. The present study examined the potential therapeutic eff
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影响因子:
5.6
作者:
Yang CH;Yen TL;Hsu CY;Thomas PA;Sheu JR;Jayakumar T
通讯作者:
Jayakumar T
影响因子:
6.2
作者:
Ray AK;DuBois JC;Gruber RC;Guzik HM;Gulinello ME;Perumal G;Raine C;Kozakiewicz L;Williamson J;Shafit-Zagardo B
通讯作者:
Shafit-Zagardo B
影响因子:
6.1
作者:
Wurzelmann M;Romeika J;Sun D
通讯作者:
Sun D
DOI:
10.1016/j.biopha.2017.05.021
发表时间:
2017-07
期刊:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
影响因子:
--
作者:
Dapeng Wang;Ke-jia Liu;Graham Kasper;Qi Lin;J. Hai
通讯作者:
Dapeng Wang;Ke-jia Liu;Graham Kasper;Qi Lin;J. Hai
影响因子:
2.7
作者:
Chern, Chang-Ming;Liou, Kuo-Tong;Shen, Yuh-Chiang
通讯作者:
Shen, Yuh-Chiang