Thermoresponsive ketoprofen-imprinted monolith prepared in ionic liquid
Thermoresponsive ketoprofen-imprinted monolith prepared in ionic liquid
复制标题
离子液体中制备的热响应酮洛芬印迹整体料
DOI：
10.1007/s00216-014-7932-3
复制
发表时间：
2014-06
影响因子：
4.3
通讯作者：
Liu Zhao-Sheng
中科院分区：
文献类型：
--
作者：
Sun Xuan;Zhao Chun-Yan;Wang Xian-Hua;Huang Yan-Ping;Liu Zhao-Sheng
A thermoresponsive imprinted monolith with the ability of molecular recognition for ketoprofen was prepared for the first time. The smart monolith was synthesized in a stainless steel column using acrylamide (AAm) and 2-acrylamide-2-methyl propanesulfonic acid (AMPS) as functional monomers, which can form interpolymer complexation to restrict access of the analyte to the imprinted networks at low temperatures. To avoid a high back pressure of the column derived from neat dimethyl sulfoxide (DMSO) as a porogenic solvent that is needed to solve polar AMPS, an ionic liquid, [BMIM]BF4, was introduced into the pre-polymerization mixture. The molecular recognition ability towards ketoprofen of the resulting thermoresponsive molecularly imprinted polymer (MIP) monolith displayed significant dependence on temperature compared with a non-imprinted column (NIP), and the greatest imprinting factor was achieved at the transition temperature of 35 °C (above 10). Furthermore, the number of binding sites of the smart MIP monolith at 35 °C was about 76 times as large as that at 25 °C. In addition, Freundlich analyses indicated that the thermoresponsive MIP monolith had homogeneous affinity sites at both 25 and 35 °C with heterogeneity index 0.9251 and 0.9851, respectively.
登录
查看更多内容
影响因子：
9.9
作者：
MCPHEE, W;TAM, KC;PELTON, R
通讯作者：
PELTON, R
DOI：
10.1016/j.chroma.2012.06.050
发表时间：
2012-08
期刊：
Journal of chromatography. A
影响因子：
--
作者：
Xiao-xia Li;Li-Hong Bai;Huan Wang;Jia Wang;Yanping Huang;Zhaosheng Liu
通讯作者：
Xiao-xia Li;Li-Hong Bai;Huan Wang;Jia Wang;Yanping Huang;Zhaosheng Liu
影响因子：
2.4
作者：
M. Zrínyi
通讯作者：
M. Zrínyi
DOI：
10.1073/pnas.0506786103
发表时间：
2006-01-31
影响因子：
11.1
作者：
Miyata, T;Jige, M;Uragami, T
通讯作者：
Uragami, T
DOI：
10.1016/s0021-9673(01)01019-6
发表时间：
2001-08
期刊：
Journal of chromatography. A
影响因子：
--
作者：
Y. Chen;M. Kele;I. Quiñones;B. Sellergren;G. Guiochon
通讯作者：
Y. Chen;M. Kele;I. Quiñones;B. Sellergren;G. Guiochon