The use of repetition suppression paradigms in developmental cognitive neuroscience

The use of repetition suppression paradigms in developmental cognitive neuroscience
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重复抑制范式在发展认知神经科学中的应用

DOI:
10.1016/j.cortex.2016.04.002
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发表时间:
2016
期刊:
影响因子:
3.6
通讯作者:
Weigelt
Weigelt
中科院分区:
心理学2区
文献类型:
--
作者:
Weigelt

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重复抑制范式比经典范式更详细地观察大脑功能,并已在成人认知神经科学中得到大力应用。这些范式非常适合发展认知神经科学领域的研究,因为它们可以在不收集行为反应的情况下应用于所有年龄组。此外,重复抑制范例可以用于各种神经科学技术,诸如功能性磁共振成像(fMRI)、功能性近红外光谱(fNIRS)、脑电图(EEG)和脑磁图(MEG)。在这篇文章中,我们回顾了使用重复抑制范式在发展认知神经科学涵盖的年龄范围从婴儿期到青春期的研究。我们的第一个目标是指出发展性重复抑制效应的特点。在这样做的时候,我们讨论了重复效应的方向(suppressionvsenhancement)与发展因素的关系,并解决这个问题,如何重复效应的方向可能与行为婴儿范式,最突出的行为措施,在婴儿研究中的时间效应。为了突出重复抑制范式的潜力,我们的第二个目标是提供一个概述的见解,最近通过应用重复范式在神经发育研究,包括自闭症谱系障碍(ASD)儿童的研究。我们的结论是,重复抑制范式是调查神经发育过程的宝贵工具,而在同一时间,我们强调进一步研究的必要性,解开方法和发展因素。
Repetition suppression paradigms allow a more detailed look at brain functioning than classical paradigms and have been applied vigorously in adult cognitive neuroscience. These paradigms are well suited for studies in the field of developmental cognitive neuroscience as they can be applied without collecting a behavioral response and across all age groups. Furthermore, repetition suppression paradigms can be employed in various neuroscience techniques, such as functional magnetic resonance imaging (fMRI), functional near-infrared spectroscopy (fNIRS), electroencephalography (EEG) and magnetoencephalography (MEG). In the present article we review studies using repetition suppression paradigms in developmental cognitive neuroscience covering the age range from infancy to adolescence. Our first goal is to point out characteristics of developmental repetition suppression effects. In doing so, we discuss the relationship of the direction of repetition effects (suppressionvsenhancement) with developmental factors, and address the question how the direction of repetition effects might be related to looking-time effects in behavioral infant paradigms, the most prominently used behavioral measure in infant research. To highlight the potential of repetition suppression paradigms, our second goal is to provide an overview on the insights recently obtained by applying repetition paradigms in neurodevelopmental studies, including research on children with autism spectrum disorders (ASDs). We conclude that repetition suppression paradigms are valuable tools for investigating neurodevelopmental processes, while at the same time we highlight the necessity for further studies that disentangle methodological and developmental factors.
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