Inactivation of primate superior colliculus impairs covert selection of signals for perceptual judgments.
Inactivation of primate superior colliculus impairs covert selection of signals for perceptual judgments.
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DOI：
10.1038/nn.2470
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发表时间：
2010-02
影响因子：
25
通讯作者：
Krauzlis, Richard J.
中科院分区：
文献类型：
--
作者：
Lovejoy, Lee P.;Krauzlis, Richard J.
灵长类动物的感知判断基于某些感官输入，而忽略其他感官输入。知觉的感觉信息的隐蔽选择通常被认为主要是由大脑皮层完成的，而对相关刺激的公开定向涉及各种额外的结构，如上丘，一个参与控制眼球运动的皮层下区域。与此观点相反，我们表明，即使在没有定向运动的情况下，上丘对于决定哪些刺激将告知感知判断是必要的。猴子在执行运动辨别任务时，上丘的可逆失活导致对受影响视野刺激的严重注意力不集中，但仅当未受影响视野中出现含有反信息信号的干扰物时。当分散注意力的刺激不包含任何信息时，辨别表现在很大程度上不受影响。因此，上丘是感知判断信号隐蔽选择的瓶颈。
Primates base perceptual judgments on some sensory inputs while ignoring others. The covert selection of sensory information for perception is often thought to be accomplished mostly by the cerebral cortex, whereas the overt orienting toward relevant stimuli involves various additional structures such as the superior colliculus, a subcortical region involved in the control of eye movements. Contrary to this view, we show that the superior colliculus is necessary for determining which stimuli will inform perceptual judgments, even in the absence of orienting movements. Reversible inactivation of the superior colliculus in monkeys performing a motion discrimination task caused profound inattention for stimuli in the affected visual field, but only when distracters containing counterinformative signals appeared in the unaffected field. When distracting stimuli contained no information, discrimination performance was largely unaffected. Thus, the superior colliculus is a bottleneck in the covert selection of signals for perceptual judgments.
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影响因子：
5.3
作者：
Hafed, Ziad M.;Goffart, Laurent;Krauzlis, Richard J.
通讯作者：
Krauzlis, Richard J.
影响因子：
2.5
作者：
JOANETTE, Y;BROUCHON, M
通讯作者：
BROUCHON, M
影响因子：
25
作者：
Ignashchenkova, A;Dicke, PW;Thier, P
通讯作者：
Thier, P
影响因子：
14.5
作者：
Mort, DJ;Malhotra, P;Husain, M
通讯作者：
Husain, M
影响因子：
25
作者：
Law, Chi-Tat;Gold, Joshua I.
通讯作者：
Gold, Joshua I.