A systematic review of patient-reported outcome measures patients with chronic limb-threatening ischemia.

A systematic review of patient-reported outcome measures patients with chronic limb-threatening ischemia.
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DOI:
10.1016/j.jvs.2021.11.057
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发表时间:
2022-05
影响因子:
4.3
通讯作者:
Conte, Michael S.
Conte, Michael S.
中科院分区:
医学2区
文献类型:
--
作者:
Goodney, Philip;Shah, Samir;Hu, Yiyuan David;Suckow, Bjoern;Kinlay, Scott;Armstrong, David G.;Geraghty, Patrick;Patterson, Megan;Menard, Matthew;Patel, Manesh R.;Conte, Michael S.

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慢性肢体威胁缺血(CLTI)引起显著的发病率,对健康相关的生活质量产生深远的负面影响。随着老龄人口中外周动脉疾病和糖尿病的患病率持续上升,CLTI对公共卫生的影响已经升级。患者报告结果测量(PROMs)已成为临床护理和研究中常见和重要的临床评价指标。PROMs对于临床效果和成本效益的衡量以及对治疗方案的共同决策非常重要。然而,用于描述CLTI患者经历的PROMs是异质的,不完整的,并且缺乏对潜在疾病过程和不同人群的特定适用性。例如,某些PROMs存在于四肢创伤患者,另一些PROMs存在于疼痛患者,还有一些PROMs存在于血管疾病患者。尽管有多种工具,但没有一种PROM包含描述CLTI患者经历所需的所有组成部分。从已发表的报告和当代该领域的大规模临床试验中可以明显看出这一重大的未满足需求。在这篇系统综述中,我们回顾了目前在临床实践和研究试验中对CLTI患者使用PROM的情况,并强调了开发用于CLTI的统一PROM仪器需要解决的差距。(中华外科杂志2022;75:1762-75。)
Chronic limb-threatening ischemia (CLTI) causes significant morbidity with profound negative effects on health-related quality of life. As the prevalence of peripheral artery disease and diabetes continue to rise in our aging population, the public health impact of CLTI has escalated. Patient-reported outcome measures (PROMs) have become common and important measures for clinical evaluation in both clinical care and research. PROMs are important for the measurement of clinical effectiveness and cost effectiveness and for shared decision-making on treatment options. However, the PROMs used to describe the experience of patients with CLTI are heterogeneous, incomplete, and lack specific applicability to the underlying disease processes and diverse populations. For example, certain PROMs exist for patients with extremity wounds, and other PROMs exist for patients with pain, and still others exist for patients with vascular disease. Despite this multiplicity of tools, no single PROM encompasses all of the components necessary to describe the experiences of patients with CLTI. This significant unmet need is evident from both published reports and contemporary large-scale clinical trials in the field. In this systematic review, we review the current use of PROMs for patients with CLTI in clinical practice and in research trials and highlight the gaps that need to be addressed to develop a unifying PROM instrument for CLTI. (J Vasc Surg 2022;75:1762–75.)
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