Solvatochromic Measurements of Mobile Phase Composition in Reversed Phase Liquid Chromatography: Polarity Values, Retention, and Stationary Phase Information
Solvatochromic Measurements of Mobile Phase Composition in Reversed Phase Liquid Chromatography: Polarity Values, Retention, and Stationary Phase Information
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反相液相色谱中流动相组成的溶剂变色测量：极性值、保留和固定相信息
DOI：
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Bruce P. Johnson
中科院分区：
文献类型：
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作者：
J. Dorsey;Bruce P. Johnson
摘要本文报道了反相液相色谱中二元甲醇-水、乙腈-水和四氢呋喃-水三种流动相的ET（30）极性值，并给出了这些溶剂任一组分极性值的计算公式。我们总结了以前报道的这些测量极性与色谱保留和亚甲基选择性的比较。通常发现，log k‘与ET（30）极性图比常用的log k’与有机改性剂百分比图更能描述保留率。对于检查的332个数据集，绘制log k'与有机改性剂百分比的平均r2值为0.9783，而绘制与ET（30）极性的平均r2值为0.9910。用二元相互作用参数与Dill提出的理论进行了比较。在甲醇-水混合物中，亚甲基选择性的变化与有机改性剂的百分比相关最好，而ET（30）极性的变化与有机改性剂的百分比相关最好。
Abstract The ET(30) polarity values of binary methanol-water, acetonitrile-water and tetrahydrofuran-water mobile phases used in reversed phase liquid chromatography are reported, and equations are presented for the calculation of polarity values for any composition of these solvents. We summarize previously reported comparisons of these measured polarities with both chromatographic retention and methylene selectivity. Plots of log k' vs. ET(30) polarity were generally found to be better descriptors of retention than commonly used plots of log k' vs. percent organic modifier. For 332 data sets examined, the average r2 value for plotting log k' vs. percent organic modifier was 0.9783 while plotting vs. ET(30) polarity gave a value of 0.9910. Retention in acetonitrile-water mixtures is also compared with theory developed by Dill using binary interaction parameters. Variation in methylene selectivity was found to correlate best with percent organic modifier in methanol-water mixtures, while the ET(30) polari...
反相液相色谱中的溶剂变色溶剂极性测量和选择性。
DOI：
10.1016/s0021-9673(01)94673-4
发表时间：
1987
期刊：
Journal of chromatography
影响因子：
--
作者：
Johnson,BP;Khaledi,MG;Dorsey,JG
通讯作者：
Dorsey,JG
反相液相色谱中的溶剂变色溶剂极性测量和保留。
影响因子：
7.4
作者：
Johnson,BP;Khaledi,MG;Dorsey,JG
通讯作者：
Dorsey,JG