An overview of recent strategies in pathogen sensing.
An overview of recent strategies in pathogen sensing.
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DOI:
10.3390/s90604483
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发表时间:
2009
期刊:
影响因子:
--
通讯作者:
Hua SZ
中科院分区:
文献类型:
--
作者:
Heo J;Hua SZ
Pathogenic bacteria are one of the major concerns in food industries and water treatment facilities because of their rapid growth and deleterious effects on human health. The development of fast and accurate detection and identification systems for bacterial strains has long been an important issue to researchers. Although confirmative for the identification of bacteria, conventional methods require time-consuming process involving either the test of characteristic metabolites or cellular reproductive cycles. In this paper, we review recent sensing strategies based on micro- and nano-fabrication technology. These technologies allow for a great improvement of detection limit, therefore, reduce the time required for sample preparation. The paper will be focused on newly developed nano- and micro-scaled biosensors, novel sensing modalities utilizing microfluidic lab-on-a-chip, and array technology for the detection of pathogenic bacteria.
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