EFFECTS OF EXPOSURE ON PREVALENCE AND CUMULATIVE RELATIVE RISK: DIRECT AND INDIRECT EFFECTS IN A RECURSIVE HAZARD MODEL.

EFFECTS OF EXPOSURE ON PREVALENCE AND CUMULATIVE RELATIVE RISK: DIRECT AND INDIRECT EFFECTS IN A RECURSIVE HAZARD MODEL.
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DOI:
10.1111/j.1467-9531.2009.01212.x
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发表时间:
2009-08-01
影响因子:
3
通讯作者:
Martin SP
Martin SP
中科院分区:
法学2区
文献类型:
--
作者:
Wu LL;Martin SP

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This paper outlines decomposition methods for assessing how exposure affects prevalence and cumulative relative risk. Let x denote a vector of exogenous covariates and suppose that a single dimension of time t governs two event processes T1 and T2. If the occurrence of the event T1 determines entry into the risk of the event T2, then subgroup variation in T1 will affect the prevalence T2, even if subgroups in the population are otherwise identical. Although researchers often acknowledge this phenomenon, the literature has not provided procedures to assess the magnitude of an exposure effect of T1 on the prevalence of T2. We derive decompositions that assess how variation in exposure generated by direct and indirect effects of the covariates x affect measures of absolute and relative prevalence of T2. We employ a parametric but highly flexible specification for baseline hazard for the T1 and T2 processes and use the resulting parametric proportional hazard model to illustrate the direct and indirect effects of family structure when T1 is age at first sexual intercourse and T2 is age at a premarital first birth for data on a cohort of nonhispanic white U.S. women.
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