Andropause symptoms and sickness absence in Japanese male workers: a prospective study
Andropause symptoms and sickness absence in Japanese male workers: a prospective study
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日本男性工人的男性更年期症状和疾病缺勤：一项前瞻性研究
DOI：
10.1080/13685538.2020.1862078
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Tsutsumi Akizumi
中科院分区：
文献类型：
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作者：
Hirokawa Kumi;Fujii Yasuhito;Taniguchi Toshiyo;Takaki Jiro;Tsutsumi Akizumi
目的探讨日本2年以上男性工人的男性更年期症状与病假的关系。方法2009年6月进行男性更年期症状基线调查，并抽血检测睾酮水平。共有418名男性（平均年龄52.4岁，SD = 8.6）参与并随访至2011年。使用Cox比例风险模型计算病假的风险比（hr）和95%置信区间（ci）。结果在随访期间，35名请病假的参与者中有31人患有身体疾病。较高的男性更年期症状评分与疾病缺勤的风险增加有关。睾酮缺乏（< 350ng /dL）与疾病缺勤无关。在男性更年期症状的亚量表中，躯体症状得分与缺勤正相关，而睾酮缺乏合并高性症状与缺勤不相关。当仅限于因身体疾病而缺勤时，结果相似。男性更年期症状与睾酮缺乏之间没有明显的相互作用。结论与睾酮缺乏无关的非特异性男性更年期症状与疾病缺勤呈正相关。
ObjectiveThe purpose of the study was to investigate the association between andropause symptoms and sickness absence in Japanese male workers over 2 years.MethodsA baseline survey asking about andropause symptoms, along with blood sampling for testosterone level, was conducted in June 2009. A total of 418 men (mean age = 52.4 years, SD = 8.6) participated and were followed through 2011. Hazard ratios (HRs) and 95% confidence intervals (CIs) for sickness absence were calculated using Cox proportional hazard models.ResultsDuring the follow-up period, 31 of 35 participants who took sickness absences had physical illnesses. A higher andropause symptom score was associated with an increased risk of sickness absence. Testosterone deficiency (<350 ng/dL) was not associated with sickness absence. Among the subscales of andropause symptoms, the somatic symptom score was positively associated with sickness absence, whereas testosterone deficiency combined with high sexual symptoms was not associated with sickness absence. Results were similar when limited to sickness absence because of physical illness. No significant interaction between andropause symptoms and testosterone deficiency was found.ConclusionsNon-specific andropause symptoms unrelated to testosterone deficiency were positively associated with sickness absence.
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