MR SIGnature MAtching (MRSIGMA) with retrospective self-evaluation for real-time volumetric motion imaging.
MR SIGnature MAtching (MRSIGMA) with retrospective self-evaluation for real-time volumetric motion imaging.
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DOI：
10.1088/1361-6560/ac2dd2
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发表时间：
2021-10-26
影响因子：
3.5
通讯作者：
中科院分区：
文献类型：
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作者：
MRSIGMA是一种实时体积MRI技术，用于放射治疗应用中实时成像肿瘤和危险器官运动，其中首先在离线训练期间计算高分辨率3D运动状态和相关运动特征的字典，然后使用快速仅特征采集和特征匹配执行实时3D成像。然而，缺乏具有相似空间分辨率和时间分辨率的参考图像为体内验证带来了重大挑战。这项工作提出了一个回顾性的自我验证MRSIGMA，其中用于实时成像的相同数据被用来创建一个非实时的比较参考。MRSIGMA与自我验证是在肝肿瘤患者中使用定量指标定义的肿瘤和附近器官的风险结构进行测试。使用实时MRSIGMA和非实时参考上定义的轮廓之间的骰子系数来评估运动成像性能。总延迟（包括信号采集和信号匹配）在250- 314 ms之间，这对于受呼吸运动影响的器官来说是足够的。对于未使用造影剂成像的患者，随时间推移的平均值±标准差dice系数为0.74 ± 0.03，对于使用造影剂成像的患者，为0.87 ± 0.03，这证明了高性能实时运动成像。MRSIGMA与自我评价提供了一种手段，执行实时体积MRI的器官运动跟踪与定量性能指标。
MRSIGMA is a real-time volumetric MRI technique to image tumor and organs at risk motion in real-time for radiotherapy applications, where a dictionary of high-resolution 3D motion states and associated motion signatures are computed first during offline training and real-time 3D imaging is performed afterwards using fast signature-only acquisition and signature matching. However, the lack of a reference image with similar spatial resolution and temporal resolution introduces significant challenges for in vivo validation. This work proposes a retrospective self-validation for MRSIGMA, where the same data used for real-time imaging are used to create a non-real-time reference for comparison. MRSIGMA with self-validation is tested in patients with liver tumors using quantitative metrics defined on the tumor and nearby organs-at-risk structures. The dice coefficient between contours defined on the real-time MRSIGMA and non-real-time reference was used to assess motion imaging performance. Total latency (including signature acquisition and signature matching) was between 250–314ms, which is sufficient for organs affected by respiratory motion. Mean ± standard deviation dice coefficient over time was 0.74 ± 0.03 for patients imaged without contrast agent and 0.87 ± 0.03 for patients imaged with contrast agent, which demonstrated high-performance real-time motion imaging. MRSIGMA with self-evaluation provides a means to perform real-time volumetric MRI for organ motion tracking with quantitative performance measures.
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影响因子：
--
作者：
Finazzi T;van Sörnsen de Koste JR;Palacios MA;Spoelstra FOB;Slotman BJ;Haasbeek CJA;Senan S
通讯作者：
Senan S
影响因子：
3.3
作者：
Feng, Li;Srichai, Monvadi B.;Lim, Ruth P.;Harrison, Alexis;King, Wilson;Adluru, Ganesh;Dibella, Edward V. R.;Sodickson, Daniel K.;Otazo, Ricardo;Kim, Daniel
通讯作者：
Kim, Daniel
影响因子：
3.4
作者：
Kerkmeijer, L. G. W.;Maspero, M.;van den Berg, C. A. T.
通讯作者：
van den Berg, C. A. T.
DOI：
10.1002/jmri.26271
发表时间：
2018-12
期刊：
Journal of magnetic resonance imaging : JMRI
影响因子：
--
作者：
Chandarana H;Wang H;Tijssen RHN;Das IJ
通讯作者：
Das IJ
影响因子：
3.5
作者：
Bjerre, Troels;Crijns, Sjoerd;Keall, Paul
通讯作者：
Keall, Paul