Highly accelerated real-time cardiac cine MRI using k-t SPARSE-SENSE.
Highly accelerated real-time cardiac cine MRI using k-t SPARSE-SENSE.
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DOI：
10.1002/mrm.24440
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发表时间：
2013-07
影响因子：
3.3
通讯作者：
Kim, Daniel
中科院分区：
文献类型：
--
作者：
Feng, Li;Srichai, Monvadi B.;Lim, Ruth P.;Harrison, Alexis;King, Wilson;Adluru, Ganesh;Dibella, Edward V. R.;Sodickson, Daniel K.;Otazo, Ricardo;Kim, Daniel
对于呼吸含量受损和/或心律不齐的患者，实时的Cine MRI可能比呼吸持有的Cine MRI更有用，但是，使用并行成像的市售实时Cine MRI方法由于其低图像采集速度，我们感受到了相对较高的空间分辨率（〜2.5mm×2.5mm）和临时分辨率（〜40ms），以产生可以在临床上应用的高质量实时Cine MR图像壁式评估和左心室（LV）功能的测量参考，呼吸持续的Cine MRI，我们的8倍加速的实时Cine MRI产生的定性级别明显较差（1-5个比例），但其图像质量和临时忠诚度得分均高于3.0（足够），文物和噪音得分是低于3.0（中度），这表明可以实现可接受的诊断图像质量。我们提出的具有K-T稀疏感的8倍加速的实时Cine MRI是快速成像心肌功能的希望。
For patients with impaired breath-hold capacity and/or arrhythmias, real-time cine MRI may be more clinically useful than breath-hold cine MRI. However, commercially available real-time cine MRI methods using parallel imaging typically yield relatively poor spatio-temporal resolution due to their low image acquisition speed. We sought to achieve relatively high spatial resolution (~2.5mm × 2.5mm) and temporal resolution (~40ms), to produce high-quality real-time cine MR images that could be applied clinically for wall motion assessment and measurement of left ventricular (LV) function. In this work, we present an 8-fold accelerated real-time cardiac cine MRI pulse sequence using a combination of compressed sensing and parallel imaging (k-t SPARSE-SENSE). Compared with reference, breath-hold cine MRI, our 8-fold accelerated real-time cine MRI produced significantly worse qualitative grades (1–5 scale), but its image quality and temporal fidelity scores were above 3.0 (adequate) and artifacts and noise scores were below 3.0 (moderate), suggesting that acceptable diagnostic image quality can be achieved. Additionally, both 8-fold accelerated real-time cine and breath-hold cine MRI yielded comparable LV function measurements, with coefficient of variation < 10% for LV volumes. Our proposed 8-fold accelerated real-time cine MRI with k-t SPARSE-SENSE is a promising modality for rapid imaging of myocardial function.
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