Bed-sharing in the absence of hazardous circumstances: is there a risk of sudden infant death syndrome? An analysis from two case-control studies conducted in the UK.

Bed-sharing in the absence of hazardous circumstances: is there a risk of sudden infant death syndrome? An analysis from two case-control studies conducted in the UK.
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DOI:
10.1371/journal.pone.0107799
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Fleming PJ
Fleming PJ
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Blair PS;Sidebotham P;Pease A;Fleming PJ

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在没有危险情况下共睡的婴儿发生婴儿猝死综合症(SIDS)的风险尚不清楚,需要进行量化。两项基于人群的SIDS婴儿病例对照研究的联合个体分析,以及年龄和最后睡眠时间可比的对照组。400名小岛屿发展中国家婴儿的父母和1386名对照者提供了1993-6年期间英国五个卫生区域(人口:1770万)和其中一个区域(2003-6年期间人口:490万)的信息。超过三分之一的SIDS婴儿(36%)在死亡时与一名成年人共睡,而在参考睡眠后,对照组婴儿的这一比例为15%(多变量OR = 3.9 [95% CI: 2.7-5.6])。与父母同睡在沙发上(OR = 18.3 [95% CI: 7.1-47.4])或与父母一起饮酒超过两个单位(OR = 18.3 [95% CI: 7.7-43.5])相关的多变量风险对所有年龄段的婴儿都非常高且显著。在3个月以下的婴儿中,与吸烟者同睡的风险显著(OR = 8.9 [95% CI: 5.3-15.1]),但在较大的婴儿中没有(OR = 1.4 [95% CI: 0.7-2.8])。对于3个月以下的婴儿(OR = 1.6 [95% CI: 0.96-2.7])来说,在没有这些危险的情况下,与同床睡觉相关的多变量风险总体上不显著(OR = 1.1 [95% CI: 0.6-2.0]),并且对较大的婴儿(OR = 0.1 [95% CI: 0.01-0.5])的保护方向相同(OR = 1.1 [95% CI: 0.6-2.0])。只有同睡者使用假人与SIDS风险较低有关,而俯卧睡眠仅与单独睡眠的婴儿风险较高有关。这些发现支持了一项公共卫生战略,强调父母应该避免特定的危险共睡环境。同睡一张沙发并不是一种安全的选择,如果父母喝酒、抽烟、吸毒,或者婴儿是早产儿,就应该避免同睡一张沙发。
The risk of sudden infant death syndrome (SIDS) among infants who co-sleep in the absence of hazardous circumstances is unclear and needs to be quantified. Combined individual-analysis of two population-based case-control studies of SIDS infants and controls comparable for age and time of last sleep. Parents of 400 SIDS infants and 1386 controls provided information from five English health regions between 1993–6 (population: 17.7 million) and one of these regions between 2003–6 (population:4.9 million). Over a third of SIDS infants (36%) were found co-sleeping with an adult at the time of death compared to 15% of control infants after the reference sleep (multivariate OR = 3.9 [95% CI: 2.7–5.6]). The multivariable risk associated with co-sleeping on a sofa (OR = 18.3 [95% CI: 7.1–47.4]) or next to a parent who drank more than two units of alcohol (OR = 18.3 [95% CI: 7.7–43.5]) was very high and significant for infants of all ages. The risk associated with co-sleeping next to someone who smoked was significant for infants under 3 months old (OR = 8.9 [95% CI: 5.3–15.1]) but not for older infants (OR = 1.4 [95% CI: 0.7–2.8]). The multivariable risk associated with bed-sharing in the absence of these hazards was not significant overall (OR = 1.1 [95% CI: 0.6–2.0]), for infants less than 3 months old (OR = 1.6 [95% CI: 0.96–2.7]), and was in the direction of protection for older infants (OR = 0.1 [95% CI: 0.01–0.5]). Dummy use was associated with a lower risk of SIDS only among co-sleepers and prone sleeping was a higher risk only among infants sleeping alone. These findings support a public health strategy that underlines specific hazardous co-sleeping environments parents should avoid. Sofa-sharing is not a safe alternative to bed-sharing and bed-sharing should be avoided if parents consume alcohol, smoke or take drugs or if the infant is pre-term.
DOI: 10.1016/s0140-6736(06)67968-3
发表时间: 2006-01-28
期刊: LANCET
影响因子: 168.9
作者:
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DOI: 10.1136/bmj.b3666
发表时间: 2009-10-13
期刊: BMJ (Clinical research ed.)
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发表时间: 2002-11-02
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发表时间: 2003-12-01
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