Classic maximum entropy recovery of the average joint distribution of apparent FRET efficiency and fluorescence photons for single-molecule burst measurements.
Classic maximum entropy recovery of the average joint distribution of apparent FRET efficiency and fluorescence photons for single-molecule burst measurements.
复制标题
用于单分子爆发测量的表观 FRET 效率和荧光光子的平均联合分布的经典最大熵恢复。
DOI:
10.1021/jp209861u
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发表时间:
2012
期刊:
影响因子:
--
通讯作者:
Johnson,CareyK
中科院分区:
文献类型:
--
作者:
DeVore,MatthewS;Gull,StephenF;Johnson,CareyK
We describe a method for analysis of single-molecule Förster resonance energy transfer (FRET) burst measurements using classic maximum entropy. Classic maximum entropy determines the Bayesian inference for the joint probability describing the total fluorescence photons and the apparent FRET efficiency. The method was tested with simulated data and then with DNA labeled with fluorescent dyes. The most probable joint distribution can be marginalized to obtain both the overall distribution of fluorescence photons and the apparent FRET efficiency distribution. This method proves to be ideal for determining the distance distribution of FRET-labeled biomolecules, and it successfully predicts the shape of the recovered distributions.
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影响因子:
2.9
作者:
Watkins, LP;Chang, HY;Yang, H
通讯作者:
Yang, H
DOI:
10.1073/pnas.96.24.13756
发表时间:
1999-11-23
影响因子:
11.1
作者:
Kask, P;Palo, K;Gall, K
通讯作者:
Gall, K
DOI:
--
发表时间:
1990
期刊:
影响因子:
--
作者:
J. Skilling
通讯作者:
J. Skilling
DOI:
10.1021/jp903671p
发表时间:
2009-08-06
期刊:
The journal of physical chemistry. B
影响因子:
--
作者:
Gopich IV;Szabo A
通讯作者:
Szabo A
影响因子:
4.4
作者:
M. Backovic;E. S. Price;Carey K. Johnson;J. Ralston
通讯作者:
J. Ralston