Asymptomatic SARS COV-2 carriers among nursing home staff: A source of contamination for residents?

Asymptomatic SARS COV-2 carriers among nursing home staff: A source of contamination for residents?
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DOI:
10.1016/j.idnow.2020.11.008
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发表时间:
2021-03
影响因子:
3.5
通讯作者:
APHP COVID 19 research collaboration
APHP COVID 19 research collaboration
中科院分区:
医学4区
文献类型:
--
作者:
Bayle C;Cantin D;Vidal JS;Sourdeau E;Slama L;Dumesges N;Trombert S;Ayllon S;Nguyen JM;Slama D;Medaghecha M;Hanon O;Salmon D;APHP COVID 19 research collaboration

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为了表明SARS-COV-2在法国养老院的传播可以来自工作人员以及居民的家庭,无论他们是否已知患有COVID-19。这项研究报告了一项对巴黎老年疗养院工作的无症状工作人员的筛查活动,该病毒在2020年3月和4月活跃传播。在筛查活动之前,有症状的COVID-19在居民中的比例为23. 3%,在其家庭雇员中的比例为12. 1%。在72小时的筛查期内,所有不知道是否感染病毒的员工均通过鼻咽拭子中的RT-PCR进行筛查。在241名接受筛查的员工中,32名(13.3%)经RT-PCR检测为SARS-CoV-2阳性。SARS-CoV-2携带者和非携带者在性别、年龄或工作人员类型方面没有差异。在75%的病例中,携带SARS-CoV-2的工作人员没有严格的症状,而在测试之后或之前的几天里,25%的人出现了COVID-19的轻微症状。考虑到有症状和无症状病例,281名家庭雇员中有66人(23. 5%)是COVID-19的携带者。对养老院无症状工作人员进行病毒携带筛查,可以避免接触和传播给经常严重脆弱的居民。
To show that circulation of SARS-COV-2 in nursing homes in France can come from staff as well as residents’ families, whether they are known or not to have had COVID-19. This study reports a screening campaign of asymptomatic staff working in elderly nursing homes in Paris where the virus had been circulating actively in March and April 2020. Before the screening campaign, the rate of symptomatic COVID-19 was 23.3% among the residents and 12.1% among their home employees. Within a 72 h screening period, all employees not known to have the virus were screened by RT-PCR in nasopharyngeal swabs. Among the 241 screened employees, 32 (13.3%) tested positive for SARS-CoV-2 on RT-PCR. SARS-CoV-2 carriers and non-carriers did not differ in term of gender, age or type of staff. Staff carrying SARS-CoV-2 were strictly asymptomatic in 75% of cases while during the days following or before the test, 25% presented mild symptoms of COVID-19. Considering both symptomatic and asymptomatic cases, 66 out of 281 (23.5%) of the home employees had been carriers for COVID-19. Screening for viral carriage of asymptomatic staff in nursing homes can avoid contact and transmission to frequently severely vulnerable residents.
DOI: 10.2807/1560-7917.es.2020.25.10.2000180
发表时间: 2020-03-12
期刊: EUROSURVEILLANCE
影响因子: 19
作者:
Mizumoto, Kenji;Kagaya, Katsushi;Chowell, Gerardo
通讯作者: Chowell, Gerardo