Prevalence of HIV, syphilis, hepatitis B, and hepatitis C among entrants to Maryland correctional facilities
Prevalence of HIV, syphilis, hepatitis B, and hepatitis C among entrants to Maryland correctional facilities
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马里兰州惩教机构进入者中艾滋病毒、梅毒、乙型肝炎和丙型肝炎的患病率
DOI：
10.1093/jurban/jth085
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
J. Vertefeuille
中科院分区：
文献类型：
--
作者：
L. Solomon;C. Flynn;Kelly L Muck;J. Vertefeuille
虽然惩教机构中丙型肝炎病毒 (HCV) 的患病率很高，但有关乙型肝炎病毒 (HBV)、HCV 和人类免疫缺陷病毒 (HIV) 合并症的数据很少，所有这些都可能使 HCV 的管理复杂化。本研究旨在估计马里兰州惩教署和巴尔的摩市拘留中心入狱人员中 HCV 患病率及其相关性。参与者包括 2002 年 1 月 28 日至 3 月 28 日期间新入狱的囚犯。从用于常规梅毒检测的样本中去除了标识符的多余血清，用于检测 HIV 和 HCV 抗体以及 HBV 表面抗原以及表面和总核心抗体。另外，所有 HIV 阳性样本均使用近期 HIV 血清转化的血清学检测算法进行了检测。在 1,081 名囚犯和 2,833 名被拘留者中，总人口的 0.6% 发现了反应性梅毒血清学检测； HIV 血清阳性率为 6.6%； HCV 患病率为 29.7%； 25.2%的被拘留者和囚犯有乙型肝炎病毒抗原或核心或表面抗体。对 HCV 阳性预测因子的多变量分析表明，被拘留者、女性、白人、老年群体、HIV 血清阳性者以及过去或现在感染 HBV 的个体更有可能 HCV 呈阳性。这些数据表明，丙型肝炎仍然是入狱人员的一个重要公共卫生问题，并且由于合并感染而变得复杂，需要解决这些问题才能进行有效治疗。
Although high prevalence of hepatitis C virus (HCV) in correctional institutions has been established, data are sparse regarding the comorbidities of hepatitis B virus (HBV), HCV, and human immunodeficiency virus (HIV), all of which may complicate the management of HCV. This study sought to estimate the prevalence and correlates associated with HCV prevalence among entrants into the Maryland Division of Correction and the Baltimore City Detention Center. Participants included all newly incarcerated entrants between January 28 and March 28, 2002. Excess sera with identifiers removed from samples drawn for routine syphilis testing were assayed for antibodies to HIV and HCV and for HBV surface antigen and surface and total core antibodies. Separately, all HIV-positive specimens were tested using the serological testing algorithm for recent HIV seroconversion. Of the 1,081 immates and 2,833 detainees, reactive syphilis serology was noted in 0.6% of the combined population; HIV seroprevalence was 6.6%; HCV prevalence was 29.7%; and 25.2% of detainees and prisoners had antigen or core or surface antibodies to HBV. A multivariate analysis of predictors of HCV positivity indicated that detainees, women, whites, older age groups, those who were HIV seropositive, and individuals with past or present infection with HBV were significantly more likely to be positive for HCV. These data indicate that hepatitis C remains an important public health concern among entrants to jail and prison and is complicated with coinfections that need to be addressed for effective treatment.
影响因子：
12.7
作者：
Garfein, RS;Vlahov, D;Nelson, KE
通讯作者：
Nelson, KE
影响因子：
120.7
作者：
Thomas, DL;Astemborski, J;Vlahov, D
通讯作者：
Vlahov, D