Titrating the Smell of Fear: Initial Evidence for Dose-Invariant Behavioral, Physiological, and Neural Responses.
Titrating the Smell of Fear: Initial Evidence for Dose-Invariant Behavioral, Physiological, and Neural Responses.
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DOI:
10.1177/0956797620970548
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发表时间:
2021-04
影响因子:
8.2
通讯作者:
Gottfried JA
中科院分区:
文献类型:
--
作者:
de Groot JHB;Kirk PA;Gottfried JA
It is well accepted that emotional intensity scales with stimulus strength. Here, we used physiological and neuroimaging techniques to ask whether human body odor—which can convey salient social information—also induces dose-dependent effects on behavior, physiology, and neural responses. To test this, we first collected sweat from 36 males classified as low-, medium-, and high-fear responders. Next, in a double-blind within-subjects functional-MRI design, 31 women were exposed to three doses of fear-associated human chemosignals and neutral sweat while viewing face morphs varying between expressions of fear and disgust. Behaviorally, we found that all doses of fear-sweat volatiles biased participants toward perceiving fear in ambiguous morphs, a dose-invariant effect generally repeated across physiological and neural measures. Bayesian dose-response analysis indicated moderate evidence for the null hypothesis (except for the left amygdala), tentatively suggesting that the human olfactory system engages an all-or-none mechanism for tagging fear above a minimal threshold.
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DOI:
10.3389/fneng.2011.00021
发表时间:
2011-11-16
期刊:
Frontiers in neuroengineering
影响因子:
--
作者:
Cleland TA;Chen SY;Hozer KW;Ukatu HN;Wong KJ;Zheng F
通讯作者:
Zheng F
影响因子:
4.6
作者:
Cecchetto, Cinzia;Lancini, Elisa;Parma, Valentina
通讯作者:
Parma, Valentina
影响因子:
9.8
作者:
Botvinik-Nezer, Rotem;Iwanir, Roni;Schonberg, Tom
通讯作者:
Schonberg, Tom
影响因子:
2.1
作者:
Hess, U;Blairy, S;Kleck, RE
通讯作者:
Kleck, RE
影响因子:
4.1
作者:
de Groot, Jasper H. B.;Semin, Gun R.;Smeets, Monique A. M.
通讯作者:
Smeets, Monique A. M.