The Human Connectome Project: A retrospective.
The Human Connectome Project: A retrospective.
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DOI：
10.1016/j.neuroimage.2021.118543
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发表时间：
2021-12-01
期刊：
影响因子：
5.7
通讯作者：
Van Essen, David C.
中科院分区：
文献类型：
--
作者：
Elam, Jennifer Stine;Glasser, Matthew F.;Harms, Michael P.;Sotiropoulos, Stamatios N.;Andersson, Jesper L. R.;Burgess, Gregory C.;Curtiss, Sandra W.;Oostenveld, Robert;Larson-Prior, Linda J.;Schoffelen, Jan-Mathijs;Hodge, Michael R.;Cler, Eileen A.;Marcus, Daniel M.;Barch, Deanna M.;Yacoub, Essa;Smith, Stephen M.;Ugurbil, Kamil;Van Essen, David C.
关键词：
The Human Connectome Project (HCP) was launched in 2010 as an ambitious effort to accelerate advances in human neuroimaging, particularly for measures of brain connectivity; apply these advances to study a large number of healthy young adults; and freely share the data and tools with the scientific community. NIH awarded grants to two consortia; this retrospective focuses on the “WU-Minn-Ox” HCP consortium centered at Washington University, the University of Minnesota, and University of Oxford. In just over 6 years, the WU-Minn-Ox consortium succeeded in its core objectives by: 1) improving MR scanner hardware, pulse sequence design, and image reconstruction methods, 2) acquiring and analyzing multimodal MRI and MEG data of unprecedented quality together with behavioral measures from more than 1100 HCP participants, and 3) freely sharing the data (via the ConnectomeDB database) and associated analysis and visualization tools. To date, more than 27 Petabytes of data have been shared, and 1508 papers acknowledging HCP data use have been published. The “HCP-style” neuroimaging paradigm has emerged as a set of best-practice strategies for optimizing data acquisition and analysis. This article reviews the history of the HCP, including comments on key events and decisions associated with major project components. We discuss several scientific advances using HCP data, including improved cortical parcellations, analyses of connectivity based on functional and diffusion MRI, and analyses of brain-behavior relationships. We also touch upon our efforts to develop and share a variety of associated data processing and analysis tools along with detailed documentation, tutorials, and an educational course to train the next generation of neuroimagers. We conclude with a look forward at opportunities and challenges facing the human neuroimaging field from the perspective of the HCP consortium.
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影响因子：
5.7
作者：
Autio JA;Zhu Q;Li X;Glasser MF;Schwiedrzik CM;Fair DA;Zimmermann J;Yacoub E;Menon RS;Van Essen DC;Hayashi T;Russ B;Vanduffel W
通讯作者：
Vanduffel W
影响因子：
5.7
作者：
Bastiani M;Cottaar M;Dikranian K;Ghosh A;Zhang H;Alexander DC;Behrens TE;Jbabdi S;Sotiropoulos SN
通讯作者：
Sotiropoulos SN
影响因子：
25
作者：
Chaarani B;Hahn S;Allgaier N;Adise S;Owens MM;Juliano AC;Yuan DK;Loso H;Ivanciu A;Albaugh MD;Dumas J;Mackey S;Laurent J;Ivanova M;Hagler DJ;Cornejo MD;Hatton S;Agrawal A;Aguinaldo L;Ahonen L;Aklin W;Anokhin AP;Arroyo J;Avenevoli S;Babcock D;Bagot K;Baker FC;Banich MT;Barch DM;Bartsch H;Baskin-Sommers A;Bjork JM;Blachman-Demner D;Bloch M;Bogdan R;Bookheimer SY;Breslin F;Brown S;Calabro FJ;Calhoun V;Casey BJ;Chang L;Clark DB;Cloak C;Constable RT;Constable K;Corley R;Cottler LB;Coxe S;Dagher RK;Dale AM;Dapretto M;Delcarmen-Wiggins R;Dick AS;Do EK;Dosenbach NUF;Dowling GJ;Edwards S;Ernst TM;Fair DA;Fan CC;Feczko E;Feldstein-Ewing SW;Florsheim P;Foxe JJ;Freedman EG;Friedman NP;Friedman-Hill S;Fuemmeler BF;Galvan A;Gee DG;Giedd J;Glantz M;Glaser P;Godino J;Gonzalez M;Gonzalez R;Grant S;Gray KM;Haist F;Harms MP;Hawes S;Heath AC;Heeringa S;Heitzeg MM;Hermosillo R;Herting MM;Hettema JM;Hewitt JK;Heyser C;Hoffman E;Howlett K;Huber RS;Huestis MA;Hyde LW;Iacono WG;Infante MA;Irfanoglu O;Isaiah A;Iyengar S;Jacobus J;James R;Jean-Francois B;Jernigan T;Karcher NR;Kaufman A;Kelley B;Kit B;Ksinan A;Kuperman J;Laird AR;Larson C;LeBlanc K;Lessov-Schlagger C;Lever N;Lewis DA;Lisdahl K;Little AR;Lopez M;Luciana M;Luna B;Madden PA;Maes HH;Makowski C;Marshall AT;Mason MJ;Matochik J;McCandliss BD;McGlade E;Montoya I;Morgan G;Morris A;Mulford C;Murray P;Nagel BJ;Neale MC;Neigh G;Nencka A;Noronha A;Nixon SJ;Palmer CE;Pariyadath V;Paulus MP;Pelham WE;Pfefferbaum D;Pierpaoli C;Prescot A;Prouty D;Puttler LI;Rajapaske N;Rapuano KM;Reeves G;Renshaw PF;Riedel MC;Rojas P;de la Rosa M;Rosenberg MD;Ross MJ;Sanchez M;Schirda C;Schloesser D;Schulenberg J;Sher KJ;Sheth C;Shilling PD;Simmons WK;Sowell ER;Speer N;Spittel M;Squeglia LM;Sripada C;Steinberg J;Striley C;Sutherland MT;Tanabe J;Tapert SF;Thompson W;Tomko RL;Uban KA;Vrieze S;Wade NE;Watts R;Weiss S;Wiens BA;Williams OD;Wilbur A;Wing D;Wolff-Hughes D;Yang R;Yurgelun-Todd DA;Zucker RA;Potter A;Garavan HP;ABCD Consortium
通讯作者：
ABCD Consortium
影响因子：
5.7
作者：
Bastiani M;Cottaar M;Fitzgibbon SP;Suri S;Alfaro-Almagro F;Sotiropoulos SN;Jbabdi S;Andersson JLR
通讯作者：
Andersson JLR
影响因子：
4.7
作者：
Casey BJ;Cannonier T;Conley MI;Cohen AO;Barch DM;Heitzeg MM;Soules ME;Teslovich T;Dellarco DV;Garavan H;Orr CA;Wager TD;Banich MT;Speer NK;Sutherland MT;Riedel MC;Dick AS;Bjork JM;Thomas KM;Chaarani B;Mejia MH;Hagler DJ Jr;Daniela Cornejo M;Sicat CS;Harms MP;Dosenbach NUF;Rosenberg M;Earl E;Bartsch H;Watts R;Polimeni JR;Kuperman JM;Fair DA;Dale AM;ABCD Imaging Acquisition Workgroup
通讯作者：
ABCD Imaging Acquisition Workgroup