Hydrogen Sulfide Plays an Important Protective Role through Influencing Endoplasmic Reticulum Stress in Diseases
Hydrogen Sulfide Plays an Important Protective Role through Influencing Endoplasmic Reticulum Stress in Diseases
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硫化氢通过影响疾病中的内质网应激发挥重要的保护作用
DOI:
10.7150/ijbs.38143
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发表时间:
2020-01
影响因子:
9.2
通讯作者:
Huiyang Liu
中科院分区:
文献类型:
--
作者:
Honggang Wang;Xingzhuo Shi;Mengyuan Qiu;Shuangyu Lv;Huiyang Liu
The endoplasmic reticulum is an important organelle responsible for protein synthesis, modification, folding, assembly and transport of new peptide chains. When the endoplasmic reticulum protein folding ability is impaired, the unfolded or misfolded proteins accumulate to lead to endoplasmic reticulum stress. Hydrogen sulfide is an important signaling molecule that regulates many physiological and pathological processes. Recent studies indicate that H2S plays an important protective role in many diseases through influencing endoplasmic reticulum stress, but its mechanism is not fully understood. This article reviewed the progress about the effect of H2S on endoplasmic reticulum stress and its mechanisms involved in diseases in recent years to provide theoretical basis for in-depth study.
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DOI:
10.1126/science.1162667
发表时间:
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期刊:
Science (New York, N.Y.)
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DOI:
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发表时间:
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