An Assessment and Quantitative Uncertainty Analysis of the Health Risks to Workers Exposed to Chromium Contaminated Soils

An Assessment and Quantitative Uncertainty Analysis of the Health Risks to Workers Exposed to Chromium Contaminated Soils
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接触铬污染土壤工人健康风险的评估和定量不确定性分析

DOI:
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发表时间:
1991
影响因子:
1.9
通讯作者:
V. Lau
V. Lau
中科院分区:
医学4区
文献类型:
--
作者:
D. Paustenbach;Deborah M. Meyer;P. Sheehan;V. Lau

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Paustenbach,Dennis J.,黛博拉·M Meyer,帕特里克J. Shee han,and Virginia Lau(1991).铬污染土壤作业工人健康风险评价及定量不确定性分析。毒理学.工业卫生。在美国北方新泽西和其他地方,数百万吨的铬铁矿加工残渣被用作填料。残留物中的主要有毒物质是三价铬[Cr(III)]和六价铬[Cr(VI)]。由于其低急性和慢性毒性,Cr(III)造成的危害可以忽略不计。相比之下,Cr(VI)被认为是高浓度的吸入性人类致癌物。北方新泽西约有40处商业和工业地产被确定为土壤中含有铬铁矿加工残留物。在这次评估中,对一个部分铺设的卡车运输码头进行了评估。土壤全铬的算术平均值和几何平均值分别为977和359 mg/kg。数据呈对数正态分布。表层土壤中Cr(VI)的算术平均值和几何平均值分别为37.6和3.1 mg/kg。数据无法拟合标准分布,可能是由于大量样品的浓度低于方法检测限(65%)。使用Monte Carlo统计模拟计算每种暴露途径的剂量。
Paustenbach, Dennis J., Deborah M. Meyer, Patrick J. Shee han, and Virginia Lau (1991). An assessment and quantitative uncertainty analysis of the health risks to workers exposed to chromium contaminated soils. Toxicol. Industrial Health. Millions of tons of chromite-ore processing residue have been used as fill in various locations in Northern New Jersey and else where in the United States. The primary toxicants in the residue are trivalent chromium [Cr(III)] and hexavalent chromium [Cr(VI)]. The hazard posed by Cr(III) is negligible due to its low acute and chronic toxicity. In contrast, Cr(VI) is considered a inhalation human carcinogen at high concentrations. Approxi mately 40 commercial and industrial properties in Northern New Jersey have been identified as containing chromite ore processing residue in the soil. One site, a partially-paved trucking terminal, was evaluated in this assessment. The arithmetic mean and geo metric mean concentrations of total chromium in soil were 977 and 359 mg/kg, respectively. The data were log-normal distrib uted. The arithmetic mean and geometric mean concentrations of Cr(VI) in surface soil were 37.6 and 3.1 mg/kg, respectively. The data could not be fit to a standard distribution, likely due to the large number of samples with concentrations below the method detection limit (65%). Dose was calculated for each exposure route using a Monte Carlo statistical simulation.
DOI: 10.1016/0013-9351(85)90074-x
发表时间: 1985-01-01
影响因子: 8.3
作者:
HEE, SSQ;PEACE, B;HAMMOND, PB
通讯作者: HAMMOND, PB