A large outbreak of COVID-19 in a UK prison, October 2020 to April 2021
A large outbreak of COVID-19 in a UK prison, October 2020 to April 2021
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2020 年 10 月至 2021 年 4 月，英国一所监狱爆发了 COVID-19 大规模疫情
DOI：
10.1101/2022.02.02.22269960
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Adamson J
中科院分区：
文献类型：
--
作者：
Adamson J
监狱很容易爆发疫情。注重隔离和群聚的控制措施会对幸福感产生负面影响。我们呈现了2020年10月至2021年4月英国威尔士一所大型男性监狱爆发的2019年冠状病毒病(新冠肺炎)疫情，并讨论了控制措施。我们收集了案例信息，包括人口统计数据、工作人员-住所邮政编码、居民牢房号码、工作区/日期、测试结果、工作人员面谈日期/笔记和居民监狱转移日期。流行病学曲线按监狱位置绘制。控制措施包括隔离(不参加工作或隔离牢房)、队列(新入院和工作区域小组)、无症状检测(发现病例)、取消公共用餐和行动限制。使用口罩和加强卫生已经到位。全基因组测序(WGS)和访谈确定了病例之间的遗传关系，传播的可信性。工作人员占53%，年龄25~34岁(女性11.5%，男性27.15%)，有症状(%)。工作人员粗发率(29%，95%可信区间26~%)高于居民(12%，95%可信区间9~15%)。全基因组测序可以帮助区分监狱中的多重介绍和人与人之间的传播。它应该尽快与无症状检测一起引入，以控制监狱疫情。及时的流行病学调查，包括数据可视化，允许进行动态风险评估和相称的控制措施，最大限度地减少居民福利的减少。
Prisons are susceptible to outbreaks. Control measures focusing on isolation and cohorting negatively affect wellbeing. We present an outbreak of coronavirus disease 2019 (COVID-19) in a large male prison in Wales, UK, October 2020 to April 2021, and discuss control measures. We gathered case-information, including demographics, staff-residence postcode, resident cell number, work areas/dates, test results, staff interview dates/notes and resident prison-transfer dates. Epidemiological curves were mapped by prison location. Control measures included isolation (exclusion from work or cell-isolation), cohorting (new admissions and work-area groups), asymptomatic testing (case-finding), removal of communal dining and movement restrictions. Facemask use and enhanced hygiene were already in place. Whole-genome sequencing (WGS) and interviews determined the genetic relationship between cases plausibility of transmission. Of 453 cases, 53% (n = 242) were staff, most aged 25–34 years (11.5% females, 27.15% males) and symptomatic (64%). Crude attack-rate was higher in staff (29%, 95% CI 26–64%) than in residents (12%, 95% CI 9–15%). Whole-genome sequencing can help differentiate multiple introductions from person-to-person transmission in prisons. It should be introduced alongside asymptomatic testing as soon as possible to control prison outbreaks. Timely epidemiological investigation, including data visualisation, allowed dynamic risk assessment and proportionate control measures, minimising the reduction in resident welfare.
影响因子：
3.9
作者：
Argimón S;Abudahab K;Goater RJE;Fedosejev A;Bhai J;Glasner C;Feil EJ;Holden MTG;Yeats CA;Grundmann H;Spratt BG;Aanensen DM
通讯作者：
Aanensen DM
Covid-19、监狱拥挤和释放政策
影响因子：
--
作者：
Paul L. Simpson;T. Butler
通讯作者：
T. Butler
可预测和不可预测的休克的躯体效应
影响因子：
3.3
作者：
J. Weiss
通讯作者：
J. Weiss