Circadian phase alteration by GABA and light differs in diurnal and nocturnal rodents during the day.
Circadian phase alteration by GABA and light differs in diurnal and nocturnal rodents during the day.
复制标题
GABA 和光引起的昼夜节律相位变化在白天和夜间啮齿动物中是不同的。
DOI：
10.1037/0735-7044.118.3.498
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Albers,HElliott
中科院分区：
文献类型：
--
作者：
Novak,ColleenM;Albers,HElliott
These studies investigated the circadian effects of light and gamma aminobutyric acid-A (GABAA) receptor activation in the suprachiasmatic nucleus (SCN) of the diurnal unstriped Nile grass rat (Arvicanthis niloticus). Microinjection of the GABAA agonist muscimol into the SCN during the day produced phase shifts that were opposite in direction to those previously reported in nocturnal rodents. In addition, light had no significant effect on the magnitude of muscimol-induced phase delays during the daytime. Injection of muscimol during the night, however, significantly inhibited light-induced phase delays and advances in a manner similar to that previously reported in nocturnal rodents. Therefore, the circadian effects of GABAA receptor activation are similar in diurnal and nocturnal species during the night but differ significantly during the day.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
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