Enhancing Research Through the Use of the Genotype-Tissue Expression (GTEx) Database.
Enhancing Research Through the Use of the Genotype-Tissue Expression (GTEx) Database.
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DOI：
10.1177/1099800421994186
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发表时间：
2021-07
影响因子：
2.5
通讯作者：
Cao X
中科院分区：
文献类型：
--
作者：
Stanfill AG;Cao X
Despite a growing interest in multi-omic research, individual investigators may struggle to collect large-scale omic data, particularly from human subjects. Publicly available datasets can help to address this problem, including those sponsored by the NIH Common Fund, such as the Genotype-Tissue Expression (GTEx) database. This database contains genotype and expression data obtained from 54 non-diseased tissues in human subjects. But these data are often underutilized, because users may find the browsing tools to be counterintuitive or have difficulty navigating the procedures to request controlled data access. Furthermore, there is limited knowledge of these resources among nurse scientists interested in incorporating such information into their programs of research. This article outlines the procedures for using the GTEx database. Next, we provide one exemplar of using this resource to enhance existing research by investigating expression of dopamine receptor type 2 (DRD2) across brain tissues in human subjects.
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影响因子：
30.8
作者：
eGTEx Project
通讯作者：
eGTEx Project
影响因子：
9.8
作者：
Learned, Katrina;Durbin, Ann;Bjork, Isabel M.
通讯作者：
Bjork, Isabel M.
影响因子：
3.7
作者：
Stanfill, Ansley;Hathaway, Donna;Conley, Yvette
通讯作者：
Conley, Yvette
影响因子：
4.4
作者：
McGuire, V.;Van den Eeden, S. K.;Tanner, C. M.;Kamel, F.;Umbach, D. M.;Marder, K.;Mayeux, R.;Ritz, B.;Ross, G. W.;Petrovitch, H.;Topol, B.;Popat, R. A.;Costello, S.;Manthripragada, A. D.;Southwick, A.;Myers, R. M.;Nelson, L. M.
通讯作者：
Nelson, L. M.
影响因子：
2.3
作者：
Stanfill A;Simpson C;Sherwood P;Poloyac S;Crago E;Kim H;Conley Y
通讯作者：
Conley Y