[A case of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) with treatment-resistant status epilepticus that was effectively treated with lamotrigine].
[A case of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) with treatment-resistant status epilepticus that was effectively treated with lamotrigine].
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[一例线粒体脑肌病、乳酸性酸中毒和中风样发作（MELAS）伴难治性癫痫持续状态，经拉莫三嗪有效治疗]。
DOI：
10.5692/clinicalneurol.53.809
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Y. Maruyama
中科院分区：
文献类型：
--
作者：
T. Kai;Shuichiro Masuda;Hiroyasu Tokunaga;Shigeaki Hayashi;T. Nagado;Y. Maruyama
一名16岁女性MELAS患者出现发热和肌阵挛性癫痫，经常规抗癫痫药物治疗后好转。由于癫痫发作在成功治疗后1个月复发，因此增加了苯巴比妥、氯硝西泮和丙戊酸盐的剂量。然而，没有改善，癫痫持续状态持续。拉莫三嗪的加入导致癫痫发作的频率降低和良好的控制。这个病例很重要，显示了拉莫三嗪治疗难治性癫痫持续状态的满意结果。
A 16-year-old woman with MELAS developed fever and myoclonic epilepsy which improved with conventional anti-epileptic drugs. Since seizures recurred one month after successful treatment, the doses of phenobarbital, clonazepan, and valproate were increased. However, there was no improvement and status epilepticus continued. The addition of lamotrigine resulted in a decreased frequency and good control of seizures. This case is important, showing satisfactory results from the addition of lamotrigine for treatment-resistant status epilepticus.
影响因子：
9.9
作者：
Koga, Y;Akita, Y;Matsuishi, T
通讯作者：
Matsuishi, T