An Official American Thoracic Society/European Respiratory Society Statement: Research Questions in Chronic Obstructive Pulmonary Disease

An Official American Thoracic Society/European Respiratory Society Statement: Research Questions in Chronic Obstructive Pulmonary Disease
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美国胸科学会/欧洲呼吸学会官方声明:慢性阻塞性肺疾病的研究问题

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发表时间:
2020
期刊:
影响因子:
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通讯作者:
R. Stockley
R. Stockley
中科院分区:
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作者:
B. Celli;M. Decramer;J. Wedzicha;K. Wilson;Alvar;Agustí;G. Criner;W. Macnee;B. Make;S. Rennard;R. Stockley

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本官方美国胸科学会(ATS)/欧洲呼吸学会(ERS)研究声明的目标是描述与诊断、评估和管理相关的证据;确定知识差距;并为未来研究提出建议。其目的不是提供关于COPD诊断和管理的临床实践建议。方法:邀请具有COPD专业知识的临床医生、研究人员和患者倡导者参加。对Medline进行了文献检索,并选择了认为相关的研究。该检索不是对证据的系统性审查。现有的证据进行了评估和总结,然后显着的知识差距identified. Results:建议的研究,解决重要的差距,在所有领域的证据COPD制定通过讨论和共识。结论:在COPD的诊断、评估和治疗以及对其发病机制的理解方面已经取得了很大的进步。尽管如此,许多重要问题仍然没有答案。本ATS/ERS研究声明强调了领先的临床医生,研究人员和患者倡导者认为将对以患者为中心的结果产生最大影响的研究类型。
goal of this Of fi cial American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Methods: Clinicians, researchers, and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarized, and then salient knowledge gaps were identi fi ed. Results: Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Conclusions: Great strides have been made in the diagnosis, assessment, and management of COPD as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS Research Statement highlights the types of research that leading clinicians, researchers, and patient advocates believe will have the greatest impact on patient-centered outcomes.
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