Musically cued gait-training improves both perceptual and motor timing in Parkinson's disease.
Musically cued gait-training improves both perceptual and motor timing in Parkinson's disease.
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DOI：
10.3389/fnhum.2014.00494
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发表时间：
2014
影响因子：
2.9
通讯作者：
Kotz SA
中科院分区：
文献类型：
--
作者：
Benoit CE;Dalla Bella S;Farrugia N;Obrig H;Mainka S;Kotz SA
众所周知，听觉提示可以改善特发性帕金森病(IPD)患者的步态。通过节拍器或音乐提供有节奏的听觉提示，可以改善与疾病相关的速度和步长的减少。然而，运动控制对认知方面的影响还有待深入研究。如果运动与听觉线索的同步依赖于涉及知觉、运动和感觉运动整合的超模式计时系统，那么听觉线索可以同时影响运动和知觉计时。在这里，我们通过评估15名IPD患者在为期4周的有节奏听觉提示音乐训练计划前后的知觉和运动计时来检验这一假设。在训练结束后1个月进行远期疗效评估( )。知觉和运动计时用电池评估听觉感觉运动和计时能力，并与年龄、性别和教育相匹配的健康对照组进行比较。在训练之前，IPD患者表现出知觉和运动计时受损。训练提高了患者在需要与同步序列同步的任务中的表现，并增强了他们在手部敲击任务中适应序列持续变化的能力。提示的好处扩展到时间感知(时长辨别和音乐摘录中未对齐节拍的检测)。目前的结果表明，听觉线索带来的好处超过了步态，并支持这样的观点，即IPD患者的步态与节奏听觉线索的耦合依赖于参与感知和运动计时的神经网络。
It is well established that auditory cueing improves gait in patients with idiopathic Parkinson’s disease (IPD). Disease-related reductions in speed and step length can be improved by providing rhythmical auditory cues via a metronome or music. However, effects on cognitive aspects of motor control have yet to be thoroughly investigated. If synchronization of movement to an auditory cue relies on a supramodal timing system involved in perceptual, motor, and sensorimotor integration, auditory cueing can be expected to affect both motor and perceptual timing. Here, we tested this hypothesis by assessing perceptual and motor timing in 15 IPD patients before and after a 4-week music training program with rhythmic auditory cueing. Long-term effects were assessed 1 month after the end of the training. Perceptual and motor timing was evaluated with a battery for the assessment of auditory sensorimotor and timing abilities and compared to that of age-, gender-, and education-matched healthy controls. Prior to training, IPD patients exhibited impaired perceptual and motor timing. Training improved patients’ performance in tasks requiring synchronization with isochronous sequences, and enhanced their ability to adapt to durational changes in a sequence in hand tapping tasks. Benefits of cueing extended to time perception (duration discrimination and detection of misaligned beats in musical excerpts). The current results demonstrate that auditory cueing leads to benefits beyond gait and support the idea that coupling gait to rhythmic auditory cues in IPD patients relies on a neuronal network engaged in both perceptual and motor timing.
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影响因子：
3.7
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