Male patients with neuromyelitis optica spectrum disorders: different clinical characteristics and worse steroid treatment response
Male patients with neuromyelitis optica spectrum disorders: different clinical characteristics and worse steroid treatment response
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男性视神经脊髓炎谱系疾病患者：不同的临床特征和较差的类固醇治疗反应
DOI：
10.1007/s10072-020-04933-1
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发表时间：
2020-11
影响因子：
3.3
通讯作者：
Qiu Wei
中科院分区：
文献类型：
--
作者：
Li Rui;Li Cong;Mao Zhifeng;Huang Qiao;Shu Yaqing;Chang Yanyu;Wang Jingqi;Wang Yuge;Qiu Wei
目的分析中国男性视神经脊髓炎(NMOSD)患者的临床特点、治疗反应和转归。方法对471例NMOSD患者的临床、人口学、治疗和转归资料进行回顾性分析。男性患者的视神经炎(ON)发作频率高于女性患者，而脊髓炎的频率低于女性患者。结论男性NMOSD患者具有不同的临床特点，对大剂量激素治疗的反应较女性差。
BackgroundClinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date.ObjectiveTo analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients.MethodsWe retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD.ResultsWe identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients.ConclusionMale NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.
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影响因子：
9.9
作者：
Wingerchuk DM;Banwell B;Bennett JL;Cabre P;Carroll W;Chitnis T;de Seze J;Fujihara K;Greenberg B;Jacob A;Jarius S;Lana-Peixoto M;Levy M;Simon JH;Tenembaum S;Traboulsee AL;Waters P;Wellik KE;Weinshenker BG;International Panel for NMO Diagnosis
通讯作者：
International Panel for NMO Diagnosis
影响因子：
9.9
作者：
Wingerchuk, D. M.;Lennon, V. A.;Weinshenker, B. G.
通讯作者：
Weinshenker, B. G.
DOI：
10.1016/s0513-5117(08)70058-9
发表时间：
2007
期刊：
Yearbook of Neurology and Neurosurgery
影响因子：
--
作者：
A. Verma
通讯作者：
A. Verma
影响因子：
14.5
作者：
Kitley, Joanna;Leite, M. Isabel;Palace, Jacqueline
通讯作者：
Palace, Jacqueline
影响因子：
9.9
作者：
D. Wingerchuk;V. Lennon;S. Pittock;C. Lucchinetti;B. Weinshenker
通讯作者：
D. Wingerchuk;V. Lennon;S. Pittock;C. Lucchinetti;B. Weinshenker