Malaria and anaemia among children in two communities of Kumasi, Ghana: a cross-sectional survey.
Malaria and anaemia among children in two communities of Kumasi, Ghana: a cross-sectional survey.
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加纳库马西两个社区儿童的疟疾和贫血：一项横断面调查。
DOI：
10.1186/1475-2875-5-105
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发表时间：
2006-11-09
期刊：
影响因子：
3
通讯作者：
Donnelly, Martin J.
中科院分区：
文献类型：
--
作者：
Ronald, Lisa A.;Kenny, Sarah L.;Klinkenberg, Eveline;Akoto, Alex O.;Boakye, Isaac;Barnish, Guy;Donnelly, Martin J.
在加纳库马西进行的一项调查发现，两个相邻社区（Moshie Zongo和Manhyia）之间的恶性疟原虫流行率存在明显差异。这项随访研究的主要目的是确定这种寄生虫率差异是否随时间推移而一致。次要目标是比较这些社区之间临床疟疾、贫血、肠道寄生虫感染和营养不良的患病率;并确定恶性疟原虫感染和贫血的潜在风险因素。2005年4月至5月，对恶性疟原虫寄生虫病、临床疟疾、贫血、人体测量指数和肠道蠕虫进行了一次逐家的横断面调查。数据收集包括儿童和家庭人口统计数据，避蚊措施，到最近的卫生设施的距离，儿童的旅行史，症状和抗疟疾药物的使用。使用广义线性混合模型确定恶性疟原虫和贫血（Hb <11 g/dl）的风险因素。总共对来自184个家庭的296名儿童进行了检测。恶性疟原虫、临床疟疾、贫血和发育迟缓的患病率在Moshie Zongo（分别为37.8%、16.9%、66.2%和21.1%）显著高于Manhyia（12.8%、3.4%、34.5%和7.4%）。在197名接受蠕虫检测的儿童中，有4名儿童的树突状双微球菌呈阳性。贫血的人群归因风险（PAR %）为16.5%（恶性疟原虫）和7.6%（营养不良）。恶性疟原虫感染的危险因素是年龄较大、农村旅行和社会经济地位较低。贫血的危险因素是恶性疟原虫感染、Moshie Zongo居住地、男性和年轻。相邻的库马西社区之间的疟疾指数的异质性是一致的，随着时间的推移。寄生虫感染率较低，恶性疟原虫感染所致贫血的PAR %比营养不良高一倍，表明疟疾是该城市人群贫血的重要原因。
A survey in Kumasi, Ghana found a marked Plasmodium falciparum prevalence difference between two neighbouring communities (Moshie Zongo and Manhyia). The primary objective of this follow-up study was to determine whether this parasite rate difference was consistent over time. Secondary objectives were to compare prevalences of clinical malaria, anaemia, intestinal parasite infections, and malnutrition between these communities; and to identify potential risk factors for P. falciparum infection and anaemia. A cross-sectional house-to-house survey of P. falciparum parasitaemia, clinical malaria, anaemia, anthropometric indices, and intestinal helminths was conducted in April-May 2005. Data collection included child and household demographics, mosquito avoidance practices, distance to nearest health facility, child's travel history, symptoms, and anti-malarial use. Risk factors for P. falciparum and anaemia (Hb < 11 g/dl) were identified using generalized linear mixed models. In total, 296 children were tested from 184 households. Prevalences of P. falciparum, clinical malaria, anaemia, and stunting were significantly higher in Moshie Zongo (37.8%, 16.9%, 66.2% and 21.1%, respectively) compared to Manhyia (12.8%, 3.4%, 34.5% and 7.4%). Of 197 children tested for helminths, four were positive for Dicrocoelium dendriticum. Population attributable risks (PAR%) of anaemia were 16.5% (P. falciparum) and 7.6% (malnutrition). Risk factors for P. falciparum infection were older age, rural travel, and lower socioeconomic status. Risk factors for anaemia were P. falciparum infection, Moshie Zongo residence, male sex, and younger age. Heterogeneities in malariometric indices between neighbouring Kumasi communities are consistent over time. The low helminth prevalence, and the twofold higher PAR% of anaemia attributable to P. falciparum infection compared to malnutrition, indicate the importance of malaria as a cause of anaemia in this urban population.
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DOI：
10.1080/00034983.1990.11812510
发表时间：
1990-12-01
影响因子：
--
作者：
LINDSAY, SW;CAMPBELL, H;GREENWOOD, BM
通讯作者：
GREENWOOD, BM
影响因子：
2.7
作者：
Omumbo, JA;Guerra, CA;Hay, SI;Snow, RW
通讯作者：
Snow, RW
影响因子：
3.3
作者：
Proux, S;Hkirijareon, L;Nosten, F
通讯作者：
Nosten, F
影响因子：
3
作者：
Donnelly MJ;McCall PJ;Lengeler C;Bates I;D'Alessandro U;Barnish G;Konradsen F;Klinkenberg E;Townson H;Trape JF;Hastings IM;Mutero C
通讯作者：
Mutero C
DOI：
10.4269/ajtmh.2004.70.245
发表时间：
2004-03-01
影响因子：
3.3
作者：
Basco, LK
通讯作者：
Basco, LK