Child height and the risk of young-adult obesity.

Child height and the risk of young-adult obesity.
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DOI:
10.1016/j.amepre.2009.09.033
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发表时间:
2010-01
影响因子:
5.5
通讯作者:
Himes, John H.
Himes, John H.
中科院分区:
医学2区
文献类型:
--
作者:
Stovitz, Steven D.;Hannan, Peter J.;Lytle, Leslie A.;Demerath, Ellen W.;Pereira, Mark A.;Himes, John H.

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儿童肥胖是成人肥胖的主要危险因素,肥胖儿童往往比正常体重的同龄人高。这项研究的目的是评估童年身高是否会影响正常或超重儿童在成年后变得超重的可能性。一项多中心前瞻性队列研究,评估对象为三年级和十二年级,n=2,802。主要暴露是CDC儿童BMI类别和三年级测量的身高四分位数。主要结果测量是CDC成人BMI类别从12年级测量。使用卡方检验和logistic回归模型评估儿童身高四分位数、儿童BMI类别和成人BMI类别之间的关系。总体而言,79%的超重儿童在成年后仍然超重。在超重或肥胖的儿童中,身高最高四分位数的儿童成为超重或肥胖青年的概率为85%,身高最低四分位数的儿童成为超重或肥胖青年的概率为67% (p = 0.007)。在体重正常的儿童中,身高最高四分位数的儿童成为超重或肥胖的可能性为25%,而身高最低四分位数的儿童为17% (p = 0.003)。当临床医生根据体重指数对儿童进行分类,并就未来肥胖的风险进行咨询时,他们应该认识到,较高的身高可能是成人超重和肥胖风险增加的标志。
Childhood obesity is a major risk factor for adult obesity, and obese children tend to be taller than their normal weight peers. The aim of the study is to evaluate whether childhood height influences the probability that normal or overweight children become overweight young adults. A multicenter prospective cohort study of subjects assessed in both 3rd grade and 12th grade, n=2,802. Main exposures were CDC childhood BMI categories and height quartiles from 3rd grade measurements. Main outcome measure was CDC adult BMI categories from 12th grade measurements. Associations between childhood height quartiles, childhood BMI categories and adult BMI categories were assessed using chi-square tests and logistic regression models. Overall, 79% of overweight children remained overweight as young adults. Among children who were overweight or obese, the probability of becoming an overweight or obese young adult was 85% for children in the top quartile of height and 67% for children in the bottom quartile of height (p = 0.007). Among children who were normal weight, the probability of becoming an overweight or obese young adult was 25% for children in the top height quartile versus 17% for children in the bottom height quartile (p = 0.003). When clinicians classify children by BMI categories and counsel about the risk for future obesity, they should recognize that greater height may be a marker for increased risk of adult overweight and obesity.
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