Human heart conjugate cooling simulation: unsteady thermo-fluid-stress analysis.
Human heart conjugate cooling simulation: unsteady thermo-fluid-stress analysis.
复制标题
DOI：
10.1002/cnm.2662
复制
发表时间：
2014-11
影响因子：
2.1
通讯作者：
Jahania MS
中科院分区：
文献类型：
--
作者：
Abdoli A;Dulikravich GS;Bajaj C;Stowe DF;Jahania MS
这项工作的主要目的是通过计算证明，通过执行共轭传热，可以更快地冷却现实的人类心脏，该共轭传热包括将冷液体泵入心室和主静脉，同时将心脏浸入填充冷却容器的冷明胶中。用于模拟的人体心脏几何形状是通过三维高分辨率 MRI 扫描获得的。为多域数值模拟定义了右（肺）和左（全身）心脏循环的两个流体流动域，以及心脏组织和明胶溶液的两个固体域。在共轭冷却过程中计算了心脏组织内详细的不稳定温度场。进行线性热弹性分析，以评估由于冷却液剪切力和法向力而施加在心脏上的应力，并检查心脏内部温度变化引起的热应力。事实证明，对于仅通过主要心脏入口静脉和腔室稳定泵送冷却剂的情况，冷却剂温度为 +4°C 的共轭冷却工作能够在 25 分钟内将平均心脏温度从 +37°C 降低至 +8°C。
The main objective of this work was to demonstrate computationally that realistic human hearts can be cooled much faster by performing conjugate heat transfer consisting of pumping a cold liquid through the cardiac chambers and major veins while keeping the heart submerged in cold gelatin filling a cooling container. The human heart geometry used for simulations was obtained from three-dimensional, high resolution MRI scans. Two fluid flow domains for the right (pulmonic) and left (systemic) heart circulations, and two solid domains for the heart tissue and gelatin solution were defined for multi-domain numerical simulation. Detailed unsteady temperature fields within the heart tissue were calculated during the conjugate cooling process. A linear thermoelasticity analysis was performed to assess the stresses applied on the heart due to the coolant fluid shear and normal forces and to examine the thermal stress caused by temperature variation inside the heart. It was demonstrated that a conjugate cooling effort with coolant temperature at +4°C is capable of reducing the average heart temperature from +37°C to +8°C in 25 minutes for cases in which the coolant was steadily pumped only through major heart inlet veins and cavities.
登录
查看更多内容
DOI：
10.1109/tuffc.2004.1320828
发表时间：
2004-05-01
影响因子：
3.6
作者：
Palmeri, ML;Nightingale, KR
通讯作者：
Nightingale, KR
影响因子：
5.3
作者：
MOORE, JE;XU, CP;KU, DN
通讯作者：
KU, DN
影响因子：
10.8
作者：
GISVOLD, SE;BRUBAKK, AO
通讯作者：
BRUBAKK, AO
影响因子：
5.6
作者：
Sterk, M;Trobec, R
通讯作者：
Trobec, R
影响因子：
4.8
作者：
Feldman, CL;Ilegbusi, OJ;Stone, PH
通讯作者：
Stone, PH