Do worsening lung ultrasound scans identify severe COVID-19 trajectories?
Do worsening lung ultrasound scans identify severe COVID-19 trajectories?
复制标题
DOI：
10.3389/fmed.2022.1021929
复制
发表时间：
2022
影响因子：
3.9
通讯作者：
中科院分区：
文献类型：
--
作者：
虽然治疗点超声(PICUS)已被用于跟踪恶化的新冠肺炎疾病，但尚不清楚严重程度轨迹之间是否存在动态差异。我们研究了244名因新冠肺炎肺炎住院的18岁≥患者[分别在3天(N=114)、7天(N=53)和每周(N=9)]进行重复扫描的12肺区扫描方案。使用线性混合效应模型比较不同严重程度峰值(由WHO临床进展分级定义)随时间变化的平均肺超声(LUS)评分和A线肺野百分比的差异。与病情较轻的住院患者相比，ICU级别或致命高峰期患者的平均LUS评分增加了0.19%(p=0.035)，A-线出现的肺野减少了14.7%(p=0.02)。在平均LUS评分0.19分(p=0.66)或A线百分比(p=0.40)方面，严重程度组之间没有差异。我们的结果不支持使用连续的LUS扫描来监测住院成人中的新冠肺炎疾病进展。
While point-of-care ultrasound (POCUS) has been used to track worsening COVID-19 disease it is unclear if there are dynamic differences between severity trajectories. We studied 12-lung zone protocol scans from 244 participants [with repeat scans obtained in 3 days (N = 114), 7 days (N = 53), and weekly (N = 9)] ≥ 18 years of age hospitalized for COVID-19 pneumonia. Differences in mean lung ultrasound (LUS) scores and percent of lung fields with A-lines over time were compared between peak severity levels (as defined by the WHO clinical progression scale) using linear mixed-effects models. Mean LUS scores were elevated by 0.19 (p = 0.035) and A-lines were present in 14.7% fewer lung fields (p = 0.02) among those with ICU-level or fatal peak illness compared to less severe hospitalized illness, regardless of duration of illness. There were no differences between severity groups in the trajectories of mean LUS score 0.19 (p = 0.66) or percent A-lines (p = 0.40). Our results do not support the use of serial LUS scans to monitor COVID-19 disease progression among hospitalized adults.
登录
查看更多内容
影响因子：
4.3
作者：
Espersen C;Platz E;Alhakak AS;Sengeløv M;Simonsen JØ;Johansen ND;Davidovski FS;Christensen J;Bundgaard H;Hassager C;Jabbari R;Carlsen J;Kirk O;Lindholm MG;Kristiansen OP;Nielsen OW;Jeschke KN;Ulrik CS;Sivapalan P;Iversen K;Stæhr Jensen JU;Schou M;Skaarup SH;Højbjerg Lassen MC;Skaarup KG;Biering-Sørensen T
通讯作者：
Biering-Sørensen T
影响因子：
2.3
作者：
Alharthy, Abdulrahman;Faqihi, Fahad;Blaivas, Michael
通讯作者：
Blaivas, Michael
护理肺超声超声预测Covid-19引起的严重疾病和死亡：一项前瞻性队列研究。
影响因子：
--
作者：
通讯作者：
--
DOI：
10.1183/13993003.04283-2020
发表时间：
2021-09
期刊：
The European respiratory journal
影响因子：
--
作者：
Rubio-Gracia J;Giménez-López I;Garcés-Horna V;López-Delgado D;Sierra-Monzón JL;Martínez-Lostao L;Josa-Laorden C;Ruiz-Laiglesia F;Pérez-Calvo JI;Crespo-Aznarez S;García-Lafuente J;Peña Fresneda N;Amores Arriaga B;Gracia-Tello B;Sánchez-Marteles M
通讯作者：
Sánchez-Marteles M
影响因子：
11.8
作者：
Brahier, Thomas;Meuwly, Jean-Yves;Boillat-Blanco, Noemie
通讯作者：
Boillat-Blanco, Noemie