Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study.

Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study.
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DOI:
10.1080/08897070903250241
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发表时间:
2009-10
期刊:
影响因子:
3.5
通讯作者:
Rounsaville BJ
Rounsaville BJ
中科院分区:
医学3区
文献类型:
--
作者:
Brewer JA;Sinha R;Chen JA;Michalsen RN;Babuscio TA;Nich C;Grier A;Bergquist KL;Reis DL;Potenza MN;Carroll KM;Rounsaville BJ

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压力在物质使用障碍(SUD)中很重要。正念训练(MT)已经显示出对压力相关疾病的承诺。没有研究将MT与经药物验证的SUD治疗进行比较。评估MT与认知行为疗法(CBT)相比在物质使用和治疗可接受性方面的差异,以及MT与CBT相比在靶向应激反应方面的特异性。36名患有酒精和/或可卡因使用障碍的人被随机分配到门诊接受MT或CBT组。每周评估药物使用情况。治疗后,测量对个性化应激激发的反应。14人完成治疗。两组之间在治疗满意度或药物使用方面没有差异。实验室范式表明,减少心理和生理指标的压力,在挑衅MT相比,CBT。这项初步研究提供了MT治疗SUD的可行性证据,并表明MT可能有效地靶向应激。
Stress is important in substance use disorders (SUDs). Mindfulness training (MT) has shown promise for stress-related maladies. No studies have compared MT to empirically-validated treatments for SUDs. to assess MT compared to cognitive behavioral therapy (CBT) in substance use and treatment acceptability, and specificity of MT compared to CBT in targeting stress reactivity. 36 individuals with alcohol and/or cocaine use disorders were randomly assigned to receive group MT or CBT in an outpatient setting. Drug use was assessed weekly. After treatment, responses to personalized stress provocation were measured. Fourteen individuals completed treatment. There were no differences in treatment satisfaction, or drug use between groups. The laboratory paradigm suggested reduced psychological and physiological indices of stress during provocation in MT compared to CBT. This pilot study provides evidence of the feasibility of MT in treating SUDs and suggests that MT may be efficacious in targeting stress.
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