Factors and reasons associated with low COVID-19 vaccine uptake among highly hesitant communities in the US.
Factors and reasons associated with low COVID-19 vaccine uptake among highly hesitant communities in the US.
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DOI：
10.1016/j.ajic.2021.12.013
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发表时间：
2022-03
影响因子：
4.9
通讯作者：
Adler-Milstein J
中科院分区：
文献类型：
--
作者：
Khairat S;Zou B;Adler-Milstein J
无法实现高新冠肺炎接种率可能会继续对我们的社区造成严重损害。疫苗接种迟疑是实现高接种率的主要障碍。我们评估了新冠肺炎疫苗接种和疫苗迟疑之间的关系，然后检查了社区因素是否与新冠肺炎疫苗接种和迟疑有关。我们构建并评估了一个横断面的县级数据集，其中包括疫苗接种率和疫苗犹豫不决的水平，以及基于疾控中心社会脆弱性指数中包括的人口特征。在美国3142个县中，疫苗迟疑率与疫苗接种率呈显著负相关(r = -0.06，P值和0.01)。在高度犹豫不决的社区中，与低疫苗接种水平相关的两个预测因素是：没有高中教育(OR：0.70，P值和.001)，以及对疫苗的可获得性和分配(CVAC)的担忧(OR：0.00，P值和.001)。导致疫苗犹豫的最常见原因是对新冠肺炎疫苗缺乏信任(55%)，其次是对疫苗副作用的担忧(48%)，以及对政府缺乏信任(46%)。新冠肺炎疫苗接种迟疑是对公众健康的威胁。我们的发现表明，低教育水平是疫苗迟疑和最终疫苗接种水平的主要原因。由于教育水平不容易改变，我们的结果表明，政策制定者最好是弥合知识差距，通过量身定做的干预措施克服对疫苗的负面看法。
The inability to achieve high COVID-19 vaccination rates can continue to have serious harm to our communities. Vaccine hesitancy is a major barrier towards high vaccination rates. We evaluated the relationship between COVID-19 vaccine uptake and vaccine hesitancy, and then examined whether community factors were associated with COVID-19 vaccine uptake and hesitancy. We constructed and evaluated a cross-sectional, county-level dataset that included the levels of vaccination uptake and vaccine hesitancy, and population characteristics based on those included in the CDC's Social Vulnerability Index. Across 3142 US counties, vaccine hesitancy was significantly and negatively correlated with vaccine uptake rates (r = -0.06, P value <.01). The 2 predictors associated with a low vaccination level within highly hesitant communities were: no high school education (OR:0.70, P value <.001), and concern on vaccine availability and distribution (CVAC) (OR:0.00, P value <.001). The most common reason driving vaccine hesitancy was lack of trust in COVID-19 vaccines (55%), followed by concerns around side effects of the vaccine (48%), and lack of trust in government (46%). COVID-19 vaccine hesitancy is a public health threat. Our findings suggest that low education levels are a major contributor to vaccine hesitancy and ultimately vaccination levels. Since education levels are not easily modifiable, our results suggest that policymakers would be best served by closing knowledge gaps to overcome negative perceptions of the vaccine through tailored interventions.
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影响因子：
4.4
作者：
Chin J;Morrow DG;Stine-Morrow EA;Conner-Garcia T;Graumlich JF;Murray MD
通讯作者：
Murray MD
影响因子：
4.8
作者：
Tan L
通讯作者：
Tan L
DOI：
10.1093/cid/ciab079
发表时间：
2021-12-16
期刊：
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子：
--
作者：
Moghadas SM;Vilches TN;Zhang K;Wells CR;Shoukat A;Singer BH;Meyers LA;Neuzil KM;Langley JM;Fitzpatrick MC;Galvani AP
通讯作者：
Galvani AP
DOI：
10.15585/mmwr.mm7023e2externalicon
发表时间：
2021-06-11
影响因子：
33.9
作者：
Christie, Athalia;Henley, Jane;Beach, Michael J.
通讯作者：
Beach, Michael J.
DOI：
10.1016/j.jamda.2021.07.034
发表时间：
2021-10
影响因子：
7.6
作者：
Khairat S;Zalla LC;Adler-Milstein J;Kistler CE
通讯作者：
Kistler CE