Fish as a Model for Research in Space

Fish as a Model for Research in Space
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鱼作为太空研究的模型

DOI:
10.1007/978-3-030-05526-4_5
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发表时间:
2022
期刊:
Handbook of Space Pharmaceuticals
影响因子:
--
通讯作者:
Akira Kudo
Akira Kudo
中科院分区:
--
文献类型:
--
作者:
Masahiro Chatani;Akira Kudo

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2012年,国际空间站(ISS)建立了一个新的饲养小鱼的设施,并进行了使用青冈鱼和斑马鱼的实验,以研究在微重力下骨丢失和肌肉萎缩的机制。首先,我们介绍了在国际空间站进行的所有小型鱼的实验,然后主要报道了最近对青冈鱼的实验。在低重力的太空飞行中,骨密度下降。为了确定这种低密度的机制,在国际空间站对青冈鱼进行了两次独特的实验。一项是分析骨骼生长的长期实验,结果显示矿物质密度有所下降。另一项是对青竹转基因品系进行活体成像的短期实验,然后进行转录组分析,结果显示有五种基因的表达增加。
A new facility for rearing small fish was established in the International Space Station (ISS) in 2012 and the experiments employing medaka fish and zebrafish were performed for studies of revealing the mechanism of bone loss and muscle atrophy under microgravity. Firstly, we introduce all experiments withsmall fish performed in the ISS, and then mainly report recent experiments for medaka fish. Space flight with low gravity shows decrease in bone mineral density. To identify the mechanism of this low density, unique experiments on medaka fish were performed twice at the ISS. One was a long-term experiment for the analysis of bone growth, which revealed a decrease in the mineral density. Another was a short-term experiment for live imaging of medaka transgenic lines followed by transcriptome analyses, which revealed increased expressions of five genes.
DOI: 10.1016/s0273-1177(98)00028-3
发表时间: 1998-01-01
期刊: LIFE SCIENCES: MICROGRAVITY RESEARCH
影响因子: --
作者:
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DOI: --
发表时间: 2015
期刊:
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DOI: 10.1016/s0273-1177(02)00398-8
发表时间: 2002
期刊: Advances in space research : the official journal of the Committee on Space Research
影响因子: --
作者:
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发表时间: 2003
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DOI: 10.2108/zsj.21.541
发表时间: 2004-05-01
期刊: ZOOLOGICAL SCIENCE
影响因子: 0.9
作者:
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通讯作者: Yamashita, I