Applying network analysis to psychological comorbidity and health behavior: Depression, PTSD, and sexual risk in sexual minority men with trauma histories.
Applying network analysis to psychological comorbidity and health behavior: Depression, PTSD, and sexual risk in sexual minority men with trauma histories.
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DOI：
10.1037/ccp0000241
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发表时间：
2017-12
影响因子：
5.9
通讯作者：
O'Cleirigh C
中科院分区：
文献类型：
--
作者：
Choi KW;Batchelder AW;Ehlinger PP;Safren SA;O'Cleirigh C
抑郁症和创伤后应激障碍的高发病率会增加性风险，特别是在童年遭受性虐待的男男性行为者（MSM）中。抑郁症和创伤后应激障碍之间的共病关系以及它们导致MSM性风险的机制尚不清楚。本研究旨在证明一种新的网络方法的可行性和实用性，以（1）描述MSM中抑郁和PTSD之间的症状相互联系，（2）识别与性风险行为相关的特定症状，（3）比较不同风险水平的群体之间的症状网络。横断面基线数据收集自296名HIV阴性城市MSM，作为多中心随机干预试验的一部分。抑郁症和创伤后应激障碍的症状是自我报告的沿着性风险行为。使用正则化偏相关网络建模在R中进行分析。网络分析揭示了抑郁症和PTSD症状之间的复杂联系，以及与性风险行为的关系。虽然症状在各自的疾病中聚集，但抑郁症和创伤后应激障碍在关键症状节点（例如，睡眠，集中）。特定症状（例如，逃避思想和感情）与性风险行为有关。跨风险群体的网络比较表明，回避过程在高风险个体中可能更容易被激活，而过度觉醒症状在低风险个体中可能更突出。这项研究是最早的抑郁症和创伤后应激障碍的网络分析之一，也是第一次将这种调查扩展到健康行为。症状水平的调查可能会澄清潜在的心理共病和行为风险的MSM和细化干预/预防目标的机制。
High rates of depression and PTSD contribute to sexual risk, particularly in men who have sex with men (MSM) who have experienced childhood sexual abuse. The comorbidity between depression and PTSD and mechanisms by which they contribute to sexual risk in MSM remain unclear. This study sought to demonstrate the feasibility and utility of a novel network approach to (1) characterize symptom interconnections between depression and PTSD in MSM, (2) identify specific symptoms related to sexual risk behavior, and (3) compare symptom networks across groups at different levels of risk. Cross-sectional baseline data were collected from 296 HIV-negative urban MSM as part of a multi-site randomized intervention trial. Symptoms of depression and PTSD were self-reported along with sexual risk behavior. Analyses were performed in R using regularized partial correlation network modeling. Network analyses revealed complex associations between depression and PTSD symptoms and in relation to sexual risk behavior. While symptoms clustered within their respective disorders, depression and PTSD were connected at key symptom nodes (e.g., sleep, concentration). Specific symptoms (e.g., avoiding thoughts and feelings) were linked to sexual risk behavior. Network comparisons across risk groups suggested avoidant processes could be more readily activated in higher-risk individuals, whereas hyperarousal symptoms may be more salient for lower-risk individuals. This study is one of the earliest network analyses of depression and PTSD, and first to extend this inquiry to health behavior. Symptom-level investigations may clarify mechanisms underlying psychological comorbidity and behavioral risk in MSM and refine targets for intervention/prevention.
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影响因子：
6.6
作者：
Chen, LS;Eaton, WW;Nestadt, G
通讯作者：
Nestadt, G
DOI：
10.1146/annurev-clinpsy-050212-185608
发表时间：
2013-01-01
期刊：
ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 9
影响因子：
--
作者：
Borsboom, Denny;Cramer, Angelique O. J.
通讯作者：
Cramer, Angelique O. J.
影响因子：
4.4
作者：
Alvy, Lisa M.;McKirnan, David J.;Hudson, Sharon
通讯作者：
Hudson, Sharon
影响因子：
7.6
作者：
Baumeister, RF;Bratslavsky, E;Tice, DM
通讯作者：
Tice, DM
影响因子：
10.3
作者：
Armour, Cherie;Fried, Eiko I.;Pietrzak, Robert H.
通讯作者：
Pietrzak, Robert H.