All-liquid separations, protein microarrays, and mass spectrometry to interrogate serum proteomes: an application to serum glycoproteomics.
All-liquid separations, protein microarrays, and mass spectrometry to interrogate serum proteomes: an application to serum glycoproteomics.
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用于询问血清蛋白质组的全液体分离、蛋白质微阵列和质谱:血清糖蛋白质组学的应用。
DOI:
10.1007/978-1-60327-811-9_6
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发表时间:
2009
期刊:
影响因子:
--
通讯作者:
Lubman,DavidM
中科院分区:
文献类型:
--
作者:
Patwa,TasneemH;Qiu,Yinghua;Zhao,Jia;Simeone,DianeM;Lubman,DavidM
Disease-related changes in serum proteins are reasonable targets for early detection particularly due to the noninvasive approach in obtaining samples. Glycoproteins specifically have been implicated in a variety of disease types ranging from immune diseases to cancers. High-throughput screening methods that can assess glycosylation states of all serum proteins in normal and diseased sample groups can facilitate early detection as well as shed light on disease progression mechanisms. Outlined here is a combination of liquid separation, protein microarray, and mass spectrometry approach to highlight candidate proteins involved in diseases through glycosylation mechanisms.
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DOI:
10.1016/s0021-9258(19)56962-9
发表时间:
1968
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
["H. Sidransky
通讯作者:
["H. Sidransky
影响因子:
11.2
作者:
K. Carroll
通讯作者:
K. Carroll
DOI:
--
发表时间:
1983
期刊:
Laboratory investigation; a journal of technical methods and pathology
影响因子:
--
作者:
Murty,CN;Hornseth,R;Verney,E;Sidransky,H
通讯作者:
Sidransky,H
DOI:
--
发表时间:
1978
期刊:
Gan
影响因子:
--
作者:
T. Kitagawa;H. Sugano
通讯作者:
H. Sugano
影响因子:
11.2
作者:
Shinozuka,H;Lombardi,B
通讯作者:
Lombardi,B