Community factors and excess mortality in first wave of the COVID-19 pandemic in England.
Community factors and excess mortality in first wave of the COVID-19 pandemic in England.
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DOI：
10.1038/s41467-021-23935-x
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发表时间：
2021-06-18
影响因子：
16.6
通讯作者：
Elliott P
中科院分区：
文献类型：
--
作者：
Davies B;Parkes BL;Bennett J;Fecht D;Blangiardo M;Ezzati M;Elliott P
COVID-19死亡风险增加的风险因素已被确定，但对社区抵御或易受大流行死亡率影响的特征知之甚少。我们应用两阶段贝叶斯空间模型量化了2020年3月至5月英格兰第一波大流行期间与2015年至2019年相比，社区层面40岁及以上人群超额死亡率的不平等。在这里，我们表明，社区的过度死亡风险增加了高密度的护理院，和/或高比例的居民收入支持，生活在过度拥挤的家园和/或与非白人种族。我们没有发现人口密度或空气污染与死亡率过高之间的联系。迫切需要针对风险最大的社区采取有效和及时的公共卫生和医疗保健措施，以避免随着大流行病的发展，死亡率模式的不平等进一步扩大。英格兰与COVID-19相关的死亡率显示出地域差异，但其原因尚不清楚。这项研究估计了大流行第一波中的超额死亡率，并发现与护理院密度较高，过度拥挤和经济贫困有关，但与人口密度或空气污染无关。
Risk factors for increased risk of death from COVID-19 have been identified, but less is known on characteristics that make communities resilient or vulnerable to the mortality impacts of the pandemic. We applied a two-stage Bayesian spatial model to quantify inequalities in excess mortality in people aged 40 years and older at the community level during the first wave of the pandemic in England, March-May 2020 compared with 2015–2019. Here we show that communities with an increased risk of excess mortality had a high density of care homes, and/or high proportion of residents on income support, living in overcrowded homes and/or with a non-white ethnicity. We found no association between population density or air pollution and excess mortality. Effective and timely public health and healthcare measures that target the communities at greatest risk are urgently needed to avoid further widening of inequalities in mortality patterns as the pandemic progresses. COVID-19-related mortality in England shows geographical variation but the reasons for this are not well understood. This study estimated excess mortality in the first wave of the pandemic and found associations with higher density of care homes, overcrowding, and economic deprivation, but not with population density or air pollution.
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影响因子：
11.8
作者：
Konstantinoudis G;Padellini T;Bennett J;Davies B;Ezzati M;Blangiardo M
通讯作者：
Blangiardo M
影响因子：
3.7
作者：
Fielding-Miller RK;Sundaram ME;Brouwer K
通讯作者：
Brouwer K
影响因子：
5.9
作者：
Cole, Matthew A.;Ozgen, Ceren;Strobl, Eric
通讯作者：
Strobl, Eric
影响因子：
7.9
作者：
Michie, Susan;West, Robert;Amlot, Richard
通讯作者：
Amlot, Richard
影响因子：
11.2
作者：
Magazzino, Cosimo;Mele, Marco;Schneider, Nicolas
通讯作者：
Schneider, Nicolas