Using oral vancomycin prescriptions as a proxy measure for Clostridium difficile infections: a spatial and time series analysis.

Using oral vancomycin prescriptions as a proxy measure for Clostridium difficile infections: a spatial and time series analysis.
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DOI:
10.1086/660858
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发表时间:
2011-07
影响因子:
4.5
通讯作者:
Cavanaugh JE
Cavanaugh JE
中科院分区:
医学4区
文献类型:
--
作者:
Polgreen PM;Yang M;Kuntz JL;Laxminarayan R;Cavanaugh JE

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一种药物的销量可能与该药物治疗的疾病的流行程度有关。我们发现,州数据显示艰难梭菌和口服万古霉素处方药销售之间存在强烈的空间关联和国家数据强烈的时间关联,这表明了一个新的检测疾病活动的“信号”。
Sales for a drug may be correlated with the prevalence of a condition treated by the drug. We found that state data revealed a strong spatial association and national data a strong temporal association between Clostridium difficile and oral vancomycin prescription sales, suggesting a new “signal” for detecting disease activity.
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