Impact of funding on biomedical research: a retrospective cohort study.
Impact of funding on biomedical research: a retrospective cohort study.
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资金对生物医学研究的影响：回顾性队列研究。
DOI：
10.1186/1471-2458-6-165
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发表时间：
2006-06-22
影响因子：
4.5
通讯作者：
Chapuis, Francois
中科院分区：
文献类型：
--
作者：
Decullier, Evelyne;Chapuis, Francois
公共资金的目的是促进研究方案的启动、完成和出版。然而，没有评估调查拨款成功对生物医学研究进行的影响。因此，比较资助协议与未资助协议的命运是非常有趣的：它们是启动的吗？它们完成了吗？结果证实了这个假设吗？它们发表了吗？目的是调查提交资助的方案的命运，无论它们是否得到资助。1997年向大里昂区域科学委员会提交资助方案的回顾性队列研究。从档案中提取方案的初始特征（设计、研究规模、研究者状态），并从邮寄给主要研究者的问卷中提取随访特征（开始、完成和发表）。在提交的142个方案中，有114个（80%）获得了随访信息。总体而言，38%的研究是由大里昂研究委员会资助的。启动率从没有确认资助的研究的62%到有委员会和其他同时资助的研究的100%不等。在启动时，至少有一项资助的研究的完成率为62%，而没有确认资助的研究的完成率为40%。在完成的研究中，有77%的研究获得了委员会资助或外部资助，58%的研究没有得到承认的资助，37%的研究同时获得了委员会和外部资助。一些提交资金的议定书是在没有宣布任何资金的情况下开始和完成的。根据我们的理解，这意味着并非所有提交的协议都真正需要资金，而且卫生保健机构没有意识到他们暗中为生物医学研究提供了财政支持和支付。
Public funding is aimed at facilitating the initiation, completion and publication of research study protocols. However, no evaluation is made to investigate the impact of grant success on the conduct of biomedical research. It is therefore of great interest to compare the fate of funded protocols versus not funded: Are they initiated? Are they completed? Did the results confirm the hypothesis? Were they published? The objective was to investigate the fate of protocols submitted for funding, whether they were funded or not. Retrospective cohort study of protocols submitted for funding to the Greater Lyon regional scientific committee in 1997. Initial characteristics of protocols (design, study size, investigator status) were abstracted from archives, and follow-up characteristics (initiation, completion and publication) from a mailed questionnaire to the principal investigators. Among the 142 submitted protocols, follow-up information was available for 114 (80%). As a whole, 38% of studies were funded by the Greater Lyon research committee. The rate of initiation varied from 62% for studies with no acknowledged funding to 100% for studies with both committee and other simultaneous funding. When initiated, the rate of completion was 62% for studies with at least one funding and 40% for studies without acknowledged funding. When completed, publication was reached for 77% of studies with either committee or external funding, for 58% of studies without acknowledged funding and for 37% of studies with both committee and external funding. Some protocols submitted for funding were initiated and completed without any funding declared. To our understanding this mean that not all protocols submitted really needed funding and also that health care facilities are unaware that they implicitly financially support and pay for biomedical research.
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影响因子：
9.8
作者：
DICK, AR;LOTT, JR
通讯作者：
LOTT, JR
影响因子：
120.7
作者：
DICKERSIN, K
通讯作者：
DICKERSIN, K
影响因子：
105.7
作者：
Decullier, E;Lheritier, V;Chapuis, F
通讯作者：
Chapuis, F
影响因子：
5.9
作者：
Druss, BG;Marcus, SC
通讯作者：
Marcus, SC
DOI：
10.1016/0197-2456(87)90155-3
发表时间：
1987-12-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DICKERSIN, K;CHAN, S;SMITH, H
通讯作者：
SMITH, H